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Flashcards in Lesson 3C (Part 5) Deck (31)
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1

What does carcinoma in-situ indicate?

That the cancer is still contained entirely with the tissue of origin and has not penetrated the tissue boundaries
- a histological diagnosis)

2

LCIS

Lobular Carcinoma In-Situ

3

Lobular Carcinoma In-Situ

Not a true cancer
- marker of significant increased future risk of developing cancer

4

What does LCIS arise from?

Small ducts of breast lobule
- multicentric, bilateral

5

What is the most common invasive cancer?

Ductal Carcinoma In-Situ

6

DCIS

Ductal Carcinoma In-Situ

7

What kind of cancer is DCIS considered?

Intraductal carcinoma

8

Intraductal carcinoma

Cancer originated within breast milk ductal epithelium and is still contained by the ductal walls

9

What age group is DCIS more common in?

50 year olds

10

How does DCIS look on US?

Microcalcifications contained within the distended duct or hypoechoic mass

11

What do 97% of patients with Pagets diseaes of the nipple have?

An underlying breast cancer

12

What are the signs and symptoms of pagets disease of the breast? (4)

1. Eczema-like rash around the nipple/areola
2. Nipple discharge
3. Itching/tingling
4. Hypersensitivity of the nipple

13

Where do most paget related breast cancers begin?

In the ducts behind the nipple

14

What are good modalities for paget disease of the breast? (2)

1. Mammography
2. Breast MRI

15

Infiltrating

Cancer has crossed multiple tissue boundaries, and is no longer contained in the tissue of origin

16

What kind of growth patterns do infiltrating lobular carcinoma have?

Diffuse growth pattern

17

How does ILC appear on US? (4)

1. Non specific parenchymal thickening
2. Irregular
3. Illdefined hypoechoic solid mass
4. Shadowing

18

What is the most common type of breast cancer?

Infiltrating ductal carcinoma
- IDC

19

Where is IDC most common located?

Upper outer quadrant

20

What does medullary carcinoma have compared to ductal or lobular carcinoma?

Better defined margins
- so is has a better prognosis

21

How does colloid carcinoma appear on US? (5)

1. Round or oval
2. Circumscribed mass
3. Lobulation or microlobulation
4. Isoechoic or hypoechoic compared to fat
5. Homogeneous or mild heterogeneous echo pattern

22

What is another term for colloid carcinoma?

Mucinous carcinoma

23

How does tubular carcinoma appear on US? (4)

1. Small irregular
2. Centrally hypoechoic mass
3. Frank spiculation
4. Surrounded by thick echogenic halo

24

What happens to Coppers ligaments with tubular carcinoma?

They become thick and straight and may cause skin retraction
- this is key

25

Inflammatory breast cancer

The cancer blocks the lymphatic drainage of the cutaneous tissues.
- rare but aggressive

26

What kind of signs come with inflammatory breast cancer? (3)

1. Reddened
2. Swollen
3. Firm breast in the absence of infection

- unexplained onsets

27

What kind of appearance do you get with inflammatory breast cancer?

Peau d’orange appearance
- orange peel

28

What is the sonographic appearance of inflammatory carcinoma? (3)

1. Microcalcifications
2. Thickened skin
3. Large axillary lymph node metastes

29

Where is the first sight of spread from primary breast cancer?

Is to the ipsilateral axillary lymph nodes

30

What is the first node in drainage basin?

Sentinel node
- at most risk for metastasis