LECTURE 5 GENETIC INHERITANCE Flashcards Preview

HUMAN GENETICS > LECTURE 5 GENETIC INHERITANCE > Flashcards

Flashcards in LECTURE 5 GENETIC INHERITANCE Deck (13)
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1

Meiosis

4 unique haploid cells from 1 diploid cell

2

Meiosis:

creates 4 non-identical haploid cells from 1 diploid cell1 round of DNA replication followed by 2 rounds of division

INTERPHASE - DNA is replicated during S Phase
MIOSIS 1 - Homologous chromosomes separated (2n -> n)
Meiosis II- Sister chromatids separated

3

Interphase:

DNA is replicated during S phase!

4

Meiosis I:

Homologous chromosomes separated

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Meiosis II

Sister chromatids separated

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Prophase I:

•Crossing over
•Creates recombinant chromosomes

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•Metaphase I:

•Homologous chromosomes line up at metaphase plate

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•Anaphase I:

•Separates homologous chromosomes
•(Mitosis separates sister chromatids)

9

Who showed autosomal traits can be dominant or recessive and which were his laws?

Mendel

- Law of Segregation
- Law of Independent Assortment

10

How different can traits controlled by one gene be inherited?

•Autosomal dominant
•Autosomal recessive
•Co-dominant alleles
•Sex-linked traits
•Maternal (mitochondrial) inheritance

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Autosomal dominant examples

•Tongue rolling
•Free earlobes
•Mid-digital hair
•Bent little finger
•Widow’s peak
•Dimples

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•Autosomal recessive

•Tongue folding
•Hitchhiker’s thumb
•Albinism

13

Sex Linked Genes

•Many more genes on X
•Recessive traits are much more commonly expressed in males

•Sex linked traits
•Color blindness
•Hemophilia