Lecture 5 Flashcards

1
Q

What is Ohm’s law?

A

This law describes that Current is equal to the voltage divided by the resistance

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2
Q

What is conductance?

A

conductance is the ease of flow

conductance and resistance are reciprocals

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3
Q

What is required for a resting membrane potential?

A
  1. a semi-permeable membrane
  2. a concentration gradient of ions across a membrane
  3. a pathway for charged ions to flow across the membrane
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4
Q

What is the steady state model?

A

A constant pumping and leakage which results in uneven distribution of key ions across the membrane

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5
Q

What is a electrochemical gradient?

A

The movement of ions based on a concentration difference and a charge difference

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6
Q

The nernst equation

A

-60/z x log (inside- outside)

This equation shows the direct relationship between energy or potential of a cell and its ions.

in equilibrium, the answer would be 0

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7
Q

What is the ion potential of Na

A

+60

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8
Q

what is the potential of K

A

-83

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9
Q

what is the potential of Ca

A

+129

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10
Q

what is the potential for Cl-

A

-66

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11
Q

What is Vm or membrane potential?

A

this is the net effect of all charge movements taking place across the membrane

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12
Q

What is E ion?

A

A calculated potential that would be generated across the membrane if that ions species were the only conductance present

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13
Q

The goldman-Hodgkin-Katz equation

A

This equation takes into account all of the ions that are permeant across a membrane.

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14
Q

Driving force equation

A

Driving force is equal to Vm - Em

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15
Q

if Vm is -83 mV and the ion is K…. what is the driving force?

A

(-83) - (-83) = 0

no driving force

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16
Q

Vm is -50 and the ion is K… what is the driving force

A

(-50) - (-83) = +33

outward net flux

17
Q

Vm is -95 and the ion is K… what is the driving force?

A

(-95) - (-83) = -12

inward net flux

18
Q

Vm is -50 mV and the ion is Na… what is the driving force?

A

(-50) - (+60) = -108

inward net flux