Lecture 2.1: Lymphoma and Leukemia - Pediatrics Flashcards Preview

Heme/Lymph Exam 1 (EH) > Lecture 2.1: Lymphoma and Leukemia - Pediatrics > Flashcards

Flashcards in Lecture 2.1: Lymphoma and Leukemia - Pediatrics Deck (10)
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1

What is the leading cause of death by disease past infancy among children in the United States?

Cancer

2

What is the most common types of cancer diagnosed in chidlren ages 0-14 y/o in the US?

Leukemias

3

What is the most common types of cancer diagnosed in adolescents 15-19 y/o; what is a common infectious agent implicated?

Lymphomas; EBV

4

Which type of lymphoma is the most common malignancy in age group 15-19 y/o?

Hodgkin lymohoma

5

What are B-symptoms?

- Unexplained fever 39°C

- Wt. loss >10% total BW over 6 months

- Drenching night sweats

6

Any pt with persistent, unexplained LAD unassociated with an obvious underlying inflammatory or infectious process should get what?

A CXR to rule of mediastinal mass before undergoing LN biopsy

7

What are the clinical manifestations of Wiscott-Aldrich Syndrome; how is it inherited; what is it a risk factor for?

- X-linked recessive

- Recurrent sino-pulmonary and ear infections

- Severe atopic dermatitis

- Bleeding --> 2' to significant thrombocytopenia

- Risk factor for NHL***

8

Burkitt lymphoma commonly manifests in pediatric populations how?

- Abdominal (sporadic type)

or

- Head and neck dz (endemic type) w/ involvement of BM or CNS

9

Which genetic trisomy associated with both ALL and AML?

Trisomy 21

10

Which type of leukemia constitutes 97% of all childhood leukemias?

Acute leukemia