Lecture 2 Flashcards
What are Halsted’s principles?
- Asepsis
- Gentle tissue handling
- Hemostasis
- Preserve blood supply
- Reduce dead space
- Avoid tension
- Anatomic dissection
Why is hemorrhage bad in surgery?
- Impaired visibility of the surgical field–> risk of iatrogenic injury, increased surgical time, poorer accuracy
- Increase risk of dead space, edema, infection
- Delays healing
- May lead to cardiovascular shock and death
What is the normal blood volume for dog/ cat?
Dog: 90ml/kg
Cat: 60 ml/ kg
When do we start to worry about blood loss?
40% severe shock, death
25% tachycardia, decrease BP
15% adequate compensation
What are the steps in clot formation
Vasoconstriction
Primary hemostasis
Secondary hemostasis
Mature thrombus
What is the main role of primary hemostasis
Formation of platelet plug ->
Endothelial cells of chemotactic platelets produce von willebrand factor
What is the role of secondary hemostasis
Formation of fibrin
What tests are in a coagulation profile
PTT test - intrinsic pathway
PT test - extrinsic pathway
Name a drug that interferes with clotting
- Acetylsalicylic acid
- warfarin toxicity - prevents formation of vit K formation which is needed for stimulation of factors 2,7,9,10
- Adequan
- Heparin
- NSAIDs
What are some acquired conditions that affect clot formation?
- Liver dz- decreased prod of clotting factors
- DIC - excessive thrombus formation, exhausts coag factors
- Biliary duct obstruction
- neoplasia
What hereditary condition affects clot formation
Von willebrands disease - Dobermans
Hemophilia A&B - sex linked/ male dogs
Thrombopathia - Bassett hounds
Problems with primary hemostasis results in ____________?
Petechia
Problems with secondary hemostasis results in _____________?
Ecchymosis
When hemorrhage occurs _________ is the first step. If it keeps bleeding it is a ______________?
Pressure
Big vessel
When do you use pressure pads to stop bleeding
For small vessels < 1mm when normal hemostasis is intact
–> require adequate pressure and time!! (1-5 min)