Lecture 17 - Membranes II Flashcards Preview

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Flashcards in Lecture 17 - Membranes II Deck (21)
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1
Q

Plasma membrane fluidity is controlled by:

a) fatty acid composition
b) saturation of fatty acids
c) position of double bonds
d) all of the above

A

d) all of the above

2
Q

Which provides more membrane fluidity, cis double bonds or trans double bonds?

A

cis (produces a bend)

3
Q

Fatty acids with longer tails have a ____ melting point.

A

higher

4
Q

Cholesterol interacts with FA tails and promotes more membrane (fluidity/stiffness)

A

stiffness

5
Q

Which of the following will occur quickly after photo bleaching?

a) lateral movement of phosphlipids
b) rapid “flip-flop” from inner to outer membrane, or vice versa.

A

lateral movement

6
Q

This cell layer provides signalling functions, cell adhesion functions, and cell identification functions.

A

glycocalyx

7
Q

Which membrane of the mitochondria is permeable to most substances?

A

outer membrane

8
Q

This structure allows for movement in and out of the nucleus

A

nuclear pore

9
Q

Which of the following is not a function of plasma membranes?

a) uptake of molecules
b) transport of molecules
c) degredation of phagocytized molecules
e) release of molecues

A

degredation of phagocytized molecules

10
Q

What protein is important in endocytosis?

A

clathrin

11
Q

Fusion of membrane bound vesicles to a synaptic neuron are assisted by what protein?

a) FRAP
b) SNARE
c) SOD-1
d) Calmodulin

A

SNARE

12
Q

Which of the following is required for proper inner mitochondrial membrane fusion?

a) formation of mitochondria to mitochondria “cross bridges”
b) large electrochemical gradient
c) large [GTP]
d) B & C

A

D) B & C

13
Q

This process salvages components of the mitochondria. It requires a sufficient electrochemical gradient and high [GTP] for hydrolysis.

A

mitochondrial fusion

14
Q

This “sorts” mitochondria to newly formed daughter cells.

A

mitochondrial fission

15
Q

Transport of proteins from ribosomes into the mitochondria is mediated by what protein set?

a) GroEL/GroES
b) HSP-90
c) HSP-70
d) . Tim/Tom System

A

D) Tim/Tom system

16
Q

Matrix targeting signals for protein translocation into the mitochondrial matrix are located on the ____ end of the nascent protein.

a) C-terminus
b) N-terminus
c) HSP-70 protein
d) Ribosome

A

B) N-terminus

17
Q

Amyloid plaques in mitochondria are a hallmark of this neurodegenerative disease

A

Alzheimer’s

18
Q

Destruction of dopaminergic neurons are a hallmark of this neurodegenerative disease.

A

Parkinson’s

19
Q

Abnormal trafficking of mitochondria away from the neuronal end are a hallmark of this disease.

A

Huntington’s

20
Q

Impairment of the electron transport chain proteins are found in this disease:

a) Alzheimer’s
b) Krutzfeldt-Jakob disease
c) Parkinson’s
d) Huntington’s

A

C) Parkinson’s

21
Q

Decreased inner mitochondrial proteins are found in this disease.

A

Alzheimer’s disease