Lecture 10: Spinal Cord and Brainstem Control of Motor Function II Flashcards

1
Q

Pyramidal system definition

A

Tracts that pass through the medullary pyramids

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2
Q

Components of pyramidal system

A

Corticospinal tract

Corticobulbar tract

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3
Q

Upper motor neurons of pyramidal system decussate where and form what

A

75-85% decussate in pyramids and form the lateral corticospinal tracts
Remainder decussate near synapse with LMN and form anterior corticospinal tracts
Most synapse with association neurons in SC central gray

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4
Q

Origins of corticospinal tract

A

Primary motor cortex
Premotor cortex
Somatosensory area

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5
Q

Pathway of corticospinal tract

A

Site of origin–> internal capule–> medullary pyramids–> X in lower medulla (most fibers)–> lateral columns of spinal cord (lateral corticospinal tract)

Some fibers do not cross but continue down ipsilaterally in ventral corticospinal tract

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6
Q

Lateral corticospinal tract made up of and supply what

A

Corticospinal fibers that have crossed in the medulla

Supply all levels of spinal cord

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7
Q

Anterior corticospinal track made up of and supply what

A

Uncrossed corticospinal fibers that cross near level of synapse with LMN
Supply neck and upper limbs

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8
Q

Functions of corticospinal tract divisions

A

Add speed and agility to conscious movements (especially in hand)
Provide high degree of motor control

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9
Q

Giant pyramidal (Bertz) cells

A

Located in motor cortex
Large fibers
Send collaterals back to cortex
Synapse directly on LMNs

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10
Q

Symptoms of cortical spinal tract lesions

A

Reduced muscle tone
Clumsiness
Weakness
Complete paralysis only occurs if both pyramidal and extrapyramidal systems are involved

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11
Q

Corticobulbar tract

A

Upper motor neurons of the cranial nerves, innervating face, head and neck

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12
Q

Corticobulbar tract fibers terminate where

A

In reticular formation near cranial nerve nuclei

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13
Q

Association neurons of corticobulbar tract synapse where

A

Cranial nerve nuclei with lower motor neurons

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14
Q

Corticobulbar tract lesions

A

Can affect hypoglossal nerve (CN XII)

Can affect facial nerve (CN VII)

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15
Q

Extrapyramidal system

A

Descending motor tracts that do not pass through medullary pyramids or corticobulbar tracts

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16
Q

Extrapyramidal system includes what tracts

A

Rubrospinal
Vestibulospinal
Reticulospinal
Olivospinal

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17
Q

Extrapyramidal subcortical nuclei (taylor)

A
Thalamus
Red nucleus
Subthalamic nucleus
Caudate
Substantia niagra
Globus pallidus
Putamen
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18
Q

Red nucleus description

A

Fibers from primary motor cortex (corticorubral pathways) and branches from corticospinal tract synapse in magnocellular portion of red nucleus

19
Q

Large neurons from magnocellular region of red nucleus give rise to

A

Rubrospinal tract which decussates in lower brain stem

20
Q

Magnocellular region has a ________ of all muscles of the body

A

Somatotopic representation

21
Q

Stimulation of red nucleus results in

A

Stimulation of flexors

Inhibition of extensors

22
Q

Red nucleus relays info from x to y (what are x/y?)

A

From motor cortex to cerebellum

23
Q

Rubrospinal tract originates, decussates, descends where

A

Originates in red nucleus
Decussates in midbrain
Descends in lateral funiculus
Function is closely related to cerebellum

24
Q

Rubrospinal tract responsible for

A

Large muscle movement and some fine motor of UE

25
Q

Lesions of rubrospinal tract cause

A

Impairment of distal arm/hand movement
Intention tremors
May take over for injured corticospinal tract in some animals

26
Q

Vestibulospinal tract originates, descends, synapses where

A

Originates in vestibular nuclei
Descends in anterior funiculus
Synapses with LMNs to extensor muscles (maintains upright posture)

27
Q

Vestibulospinal tract receives input from

A
Vestibular nerve (CN VIII) about changes in head position
Helps maintain balance
28
Q

Lateral vestibulospinal tract characteristics

A

Major part of tract
Ipsilateral
To lumbar region of SC
Upright posture/balance (extensors of LE/trunk)

29
Q

Medial vestibulospinal tract characteristics

A

Projects bilaterally

30
Q

Reticulospinal tract originates/descends

A

In reticular formation

Descends in lateral funiculus (column)

31
Q

Functions of reticulospinal tract

A
Mediates larger movement of trunk/limbs
Excites axial extensors when standing
Controls alpha/gamma motor neurons
Mediates autonomic functions (breathing)
Can modulate pain
32
Q

Pontine reticular nuclei

A

Make up anterior column

Stimulatory effect on both extensors/flexors but mostly extensors

33
Q

Medullary reticular nuclei

A

Make up lateral column

Inhibitory effect on both extensors/flexors but mostly extensors

34
Q

Semicircular canals detect ___ while utricle and saccule detect

A

Semicircular canals detect angular acceleration of head

Utricle and saccule detect linear acceleration of head

35
Q

Utricle and saccule each contain

A

Macula which contains hair cells

36
Q

Semicircular canal contains

A

Enlargement at one end called ampulla which has hair cells

37
Q

Function and plane of macula of utricle

A

Horizontal plane

Determining orientation of head when head is upright

38
Q

Function and plane of macula of saccule

A

Vertical plane

Signals head orientation when person is lying down

39
Q

Statoconia

A

Calcium carbonate crystals in macula

The weight of these crystals bend cilia in direction of gravitational pull

40
Q

Bending of stereocilia towards kinocilium does what

A

Opens hundreds of cation channels causing receptor membrane depolarization/excitation

41
Q

Bending of cilia in opposite direction of kinocilium does what

A

Closes channels and hyperpolarizes receptor membrane

42
Q

Semicircular canal fluid function

A

Fluid flows through the ampulla and causes cupula to bend to one side
Hair cells within cupula detect bending and send signals via vestibular nerve

43
Q

Ampulla characteristics

A

Filled with endolymph
Contains crista ampullaris
Contains cupula above the crista

44
Q

Response of hair cell in semicircular canal with head rotation

A

At onset of rotation, cupula is dragged through endolymph and cilia are bent-depolarization
When head stops, endolymph continues moving and cilia are bent in opposite direction causing hyperpolarization