Klebsiella - Exam 2 Flashcards Preview

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Flashcards in Klebsiella - Exam 2 Deck (17)
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1
Q

Klebsiella is a gram _____ bacteria.

A

Negative

2
Q

Which virulence factor of Klebiella is responsible for fever, neutropenia, petechia and shock?

A

Endotoxin - lipid A

3
Q

Which virulence factor is essential to Kelbsiella and binds to epithelial cells in urinary and respiratory tracts?

A

The capsule

4
Q

What is the most common bacterial isolate from non-human primates with pneumonia?

A

K. pneumoniae

5
Q

How is Klebsiella transmitted?

A

Many species it is transferred by wound infections, especially when skin or mucosae are breached by dz, trauma, burns, ect

6
Q

What economincally significant disease does Klebsiella cause in ruminants?

A

Bovine mastitis

Case fatality as high at 80%

7
Q

What diseases does Klebsiella cause in horses?

A

Reproductive tract disease (vaginitis, inferitilty, metritis and abortion)

Navel ill (common in animals that failed passive transfer)

8
Q

What are the diseases that Klebsiella commonly causes in dogs?

A

Pyometra, systitis, prostatitis, meningoencephalitis, enteritis, mastitis and hepatic abcessation

9
Q

What diseases does Klebsiella cause in pet birds?

A

Respiratory infections, septicemia and diarrhea

10
Q

What diseases does Klebsiella cause in reptiles?

A

Pneumonia and hypopyon

(hypopyon - inflammatory cells in the anterior chamber of eye)

11
Q

What does Klebsiella cause in guinea pigs?

A

Septicemia

12
Q

What makes the bacteria more invasive and more resistant to phagocytosis?

A

Capsular serotypes K1 and K2 that carry genes MagA and rmpA

(MagA - mucoviscosity-associated gene/K1 specific capsular polymerase gene)

(rmpA - regulator of mucoid phenotype)

13
Q

What causes septic shock with Klebsiella?

A

DIC

14
Q

What species of monkeys in St. Kitts is Klebsiella prevalent in?

A

Vervet monkeys

Abscesses everywhere found in a Vervet onkey with pus present in the abdominal cavity

15
Q

What is indicative of capsule ona bacteriological culture of Klebsiella?

A

Large mucoid viscous colonies on blood agar

16
Q

How would you prevent and control Klebsiella for cows?

A

Avoid sawdust or wood shaving bedding

17
Q

How do you prevent nosocomial infectinos of Klebsiella?

A

Improve hand washing, sterilization procedures, closed-system urinary drainage, reduce prophylactic use of antibiotics