JAALAS 2011 No. 3 Flashcards

1
Q
  1. What is the genus/species of the Syrian hamster?
A

Mesocricetus auratus

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2
Q
  1. How does the Siberian hamster differ from the Syrian hamster physiologically?
A
  1. Siberian is half the size, has furred feet, has coat color change to white in the winter vs. dark in the summer in the wild, and has large litters year around (vs. variable seasonality seen in Syrians).
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3
Q
  1. What is one non-renal cause of the elevated BUN in the males that the authors listed as possible, but did not find any evidence of?
A

Gastrointestinal bleeding

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4
Q

Can the values from this study be used as reference values to improve characterization of cardiac disease in New Zealand rabbits?

A

Yes

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5
Q

What do the acronyms TDI and TV stand for?

A

Tissue Doppler imaging and tissue velocity imaging

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6
Q

T/F. Echocardiographic parameters are not affected by body weight

A

This paper suggests that M-mode measurements may be dependent on body size (as is in dogs).

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7
Q

The most frequent lesions in the Raccoons examined in this study were present in

a. Brain, Heart, Liver
b. Brain, Heart, Uterus
c. Heart, Uterus, Liver
d. Uterus, Spleen, Liver

A

b. Brain, Heart, Uterus

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8
Q

What stain is used for detection of Iron in tissues?

a. Congo Red
b. H & E
c. Pearl Prussian Blue
d. Masson Trichrome

A

c. Pearl Prussian blue

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9
Q

Which of the following lesions reported in this study has never been previously documented in Raccoons?

a. Inflammatory cell infiltrates in choroid plexus
b. Lymphocytic gastritis with bacteria
c. Lafora bodies in brain
d. All the above
e. None of the above

A

D

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10
Q

True or False. Lafora bodies have been previously documented in dogs and few other domestic animals.

A

True

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11
Q

True or False. Islet cell amyloidosis previously documented in aged captive Raccoons animals was a common finding in this study also.

A

False

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12
Q

True or False. Life expectancy of free ranging raccoons can exceed 10 years.

A

False

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13
Q
  1. True or False. The sensitivity of the fur pluck technique for detecting Mycoptes sp. is decreased when the mouse cage density is low.
A

True

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14
Q
  1. True or False. The fur pluck technique is superior to the sticky paper technique for the detection of Mycoptes musculinus in the mouse.
A

False

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15
Q
  1. What is the length of the life cycle for Mycoptes musculinus and Myobia musculi?
A
  1. Mycoptes musculinus 8-14 days; Myobia musculi 23 days
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16
Q
  1. Select the following true statement about a drug’s hepatic extraction ratio:
    a. A drug with a hepatic extraction ratio of close to 1 means that hepatic blood flow has little to no effect on clearance of the drug
    b. A drug with a hepatic extraction ratio of close to 1 means that drug clearance is related to and highly dependent on hepatic blood flow
    c. Hepatic extraction ratio has nothing to do with hepatic drug clearance.
    d. None of the above
A

B

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17
Q
  1. Select the following true statement about fasting prior to Ketamine/Xylazine (KX) anesthesia in rats:
    a. Fasting is shown to have a profoundly positive effect on the quality of KX anesthesia in rats.
    b. Fasting prior to KX anesthesia in rats is detrimental to the rat.
    c. Fasting prior to administration of KX anesthesia has not been shown to affect quality or variability of KX anesthesia in the rat
    d. Fasting rats is necessary prior to inhalant anesthesia, but not prior to KX anesthesia
A

C

18
Q
  1. Why are volatile gas anesthetics contra-indicated for ischemia-reperfusion studies?
A
  1. Volatile anesthetics can protect tissues (including heart, brain, kidney, lung & liver) from ischemia-reperfusion injury.
19
Q

For the acetic acid test, what substance provided the most increase in nocioceptive threshold in Xenopus laevis?

A

Flunixin meglumine at 25 mg/kg

20
Q

The AAT and Hargreaves tests both measure response to what type of stimuli?

 	a. Visceral pain
 	b. Cutaneous stimulation of afferent fibers
A

b. Cutaneous stimulation of afferent fibers

21
Q

Describe the Hargreaves apparatus.

A

The Hargreaves apparatus is used to measure thermal nociceptive threshold. It consists of a glass chamber though which a radiant heat source is focused on an area. In this case, frogs were placed in the chamber, and an infrared intensity was focused on the inner thigh. The time from activation of the thermal stimulus to withdrawal response was recorded as the thermal nociceptive threshold.

22
Q

Surgical intestinal resection may be a useful tool for studies in?

a. Metabolism
b. Intestinal microbiology
c. Immunity
d. All of the above

A

D

23
Q

Which of these would be considered artiodactyl species?

a. Sheep
b. Pig
c. Horse
d. a and b

A

D

24
Q

What portion of the small intestine in swine contains continuous Peyer patches?

a. Ileum
b. Jejunum
c. Duodenum
d. b and c

A

A

25
Q

What is the normal gestation of a pig?

a. 90-91 days
b. 110-111 days
c. 114-115 days
d. 120-122 days

A

C

26
Q

What is the common name for a female goat?

a. Buck
b. Doe
c. Jill
d. Kid
e. Kit

A

B

27
Q

True or False. The intraosseous device may be placed without local anesthetic.

A

True

28
Q

In human medicine, collection of urine for urine:protein creatinine clearance is traditionally done over a period of how many hours?

A

24 hours

29
Q

Name the genus and species of the chimpanzee?

A

Pan troglodytes

30
Q

What 2 factors impacted the UPC ratio?

a. Age and gender
b. Age and blood contamination
c. Blood contamination and gender
d. Hepatitis infection status and gender

A

Age and blood contamination

31
Q
  1. Modified Twort is what type of special stain used in this study?
A

Gram stain

32
Q
  1. NCr-nu/nu mice lack _____and are_____.
    a. B cells; outbred
    b. T cells; outbred
    c. B cells; inbred
    d. T cells; inbred
A

B

33
Q

T/F. This study highlights the importance of performing PK studies prior to extra label drug usage.

A

True

34
Q

T/F. Cefovecin should not be used in NHPs due to high incidence of adverse effects noted in these species.

A

False

35
Q

T/F. According to this study, the use of long-acting antibiotics in NHPs is generally discouraged.

A

False

36
Q
  1. What types of sweat glands are found in the paw pad of dogs?
A
  1. Eccrine glands: an unbranched, tubular gland, limited to the footpad and the nose.
37
Q
  1. What type of innervation is associated with sweat glands, sympathetic or parasympathetic?
A

Sympathetic: acetylcholine is the neurotransmitter associated with the sweat glands.

38
Q
  1. What is the typical clinical sign observed animals with subclavian steal phenomenon?
    a. Lethargy
    b. Asymptomatic
    c. Vomiting
    d. Syncope
A

B

39
Q
  1. What is the normal blood pressure of a rhesus macaque?
A

125/75 mm Hg

40
Q
  1. What methods may be used to definitively diagnose subclavian steal phenomenon?
    a. CAT scan with contrast
    b. MRI
    c. Ultrasound
    d. All of the above
A

D

41
Q

Describe the typical progression from precancerous epithelium to cancer.

A

Epithelial cell hyperplasia → squamous metaplasia (typically with dysplasia) → carcinoma → neoplasia

42
Q

Thyroid Transcription Factor 1 is normally present in which non-thyroid tissue?

a. Lung
b. Liver
c. Spleen
d. Kidney

A

A