Intro to Therapeutics Flashcards Preview

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Flashcards in Intro to Therapeutics Deck (6)
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1
Q

What are the principals of pharmacology

A
  • The relationship between drug concentration and biological response
  • Drug action over time
  • Factors affecting absorption, distribution, binding, metabolism and elimination of drugs
  • Biological changes that result from repeated drug use: tolerance, addiction, adverse reactions, altered rates of metabolism etc
  • Antagonism of the effects of one drug by another
  • Receptor theory
2
Q

What drug concentrations are needed for efficacy?

A

The THERAPEUTIC RANGE of drug plasma concentrations

3
Q

what is Pharmacodynamics?

A

“What the drug does to the body”

4
Q

In vitro dose response studies tell us?

A

what concentration of drug is needed

5
Q

What determines pharmacokinetics?

A

The four processes of ADME determine the plasma concentration of drug over time

6
Q

what is PHARMACOKINETICS?

A

the study of drug disposition ie. “What the body does to a drug”.