Infectious Disease, Exotic Conditions, Bioterror Flashcards Preview

Bioscience II > Infectious Disease, Exotic Conditions, Bioterror > Flashcards

Flashcards in Infectious Disease, Exotic Conditions, Bioterror Deck (16)
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1

What is the primary bacteria involved in tuberculosis?

Mycobacterium tuberculosis; obligate aerobe

2

What % of TB cases occur in the lungs?

~90%

3

What are the 4 most common s\s of TB?

fever, weight loss, night sweats, fatigue

4

What is the Mantoux Skin Test?

skin test for TB

5

When does the results of the mantoux skin test need to be examined?

within 48-72 hours

6

What indicates a positive mantoux skin test? HIV patients?

induration > 10mm; AIDS induration > 5mm

7

What presentation on a chest radiograph is indicative of severe tuberculosis?

cavitation

8

Where will infiltrates most commonly be seen on a chest radiograph?

apical infiltrates

9

What are the 2 most common antibiotics prescribed for TB?

rifampicin and isoniazid

10

Why is it suggested that only "highly susceptible" populations or individuals receive the TB vaccination (bacillus Calmette-Guerin--BCG)?

it makes the TB skin test falsely positive; may not confer immunity (and the immunity it does induce decreases after 10 years)

11

Which toxin involved in c-diff is the most cytotoxic?

Toxin B is 1000x more cytotoxic than A

12

After how many days of antibiotic therapy does a patients risk of c-diff double?

after 3 days

13

What is the difference in c-diff colonization and infection?

both test + for c-diff organism and/or toxin; colonization is MORE COMMON; infection occurs with + test and presentation of clinical symptoms: watery diarrhea, fever, loss of appetite, nausea, abdominal pain/distention

14

What is the primary cause of malaria?

parasitic protozoans of genus Plasmodium; female mosquito (anopheles gambiae)

15

CDC has identified 3 categories of bioterror agents and diseases. What are included in these categories?

A: anthrax, botulism, plague, smallpox, tularemia, viral hemorrhagic fevers
B: brucellosis, food safety threats, ricin toxin
C: emerging diseases such as Hanta virus or Nipah virus

16

What are the main differences in the CDC classes for bioterror agents?

A: highest priority... easily disseminated or transmissible... high mortality
B: moderately easy to disseminate; moderate morbidity and low mortality
C: emerging pathogens with potential for availability, easy of production/dissemination, high morbidity and mortality