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Flashcards in Infections - Viral Deck (24)
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1
Q

Generalised palpable lymphadenopathy is present with CD4+ cell counts of >500/mm3 (ie. stage I HIV)

A

True `

2
Q

Primary HIV exanthem is also known as the acute retroviral syndrome

A

True

3
Q

HIV infected women have a 3 x increased risk of CIN

A

True

4
Q

HIV parasite associations

A

Leishmanisis
Strongyloides
Acanthamebiasis
Scabies

5
Q

Leishmanisis in HIV has a higher rate of therapeutic failure

A

True

6
Q

HIV induces a shift from a protective Th1 to a Th-type reaction pattern in leishmanisis

A

True

7
Q

List HIV related dermatoses that are not infectious in nature

A
Seb derm
Psoriasis
Reactive arthritis
Xerosis
PRP type VII
Pruritic papules eruption of HIV
Eosinphilic folliculitis HIV associated
8
Q

Hair and nail disorders secondary to HIV include TRICHOMEGALY due to prolonged anagen resulting from IFNa and zidovudine

A

True

9
Q

Nail changes are uncommon in HIV patients

A

False common in 2/3

10
Q

HIV Pt have same risk of developing merkel cell ca and sebaceous ca

A

False, elevated

11
Q

IRIS occurs 1wk to 3 mo after ART with higher risk in those with high CD4+ T cell counts perior to therapy

A

False in low CD4+ T cell counts <50/mm3

12
Q

Condyloma lata are moist flat papules/plaques with macerated eroded surfaces in intertriginous areas

A

True

13
Q

HSV is often acquired asymptomatic ally

A

T

14
Q

Grouped blisters on buttocks almost always HSV1

A

False HSV2

15
Q

Complications of genital herpes

A
Neuropathic bladder
Enhanced HIV transmission due to ulcer
Psychosocial morbidity
Neonatal herpes
Aseptic meningitis
16
Q

First ep of HSV needs Valtrex 500mg BD for 5-10 days or acyclovir 400mg TDS for 5-10days

A

True

17
Q

How to perform a Tzanck smear

A

Deroof blister with blunt edge of scalpel blade,
Scrape base of lesion
Smear tissue on clean microscope thinly
Allow to dry, fix specimen with preservative (either alcohol or heat)

18
Q

Chance of baby being infected with HSV in setting of genital herpes

A

Very very low, in setting of recurrent infection <3% due protective transplacental antibody. If primary genital herpes, risk is 25-50% for vaginal delivery . Might need acyclovir closer to pregnancy or opt for C section

19
Q

HPV strains that cause anogenital warts are which subtypes?

A
  • HPV 6 and 11
20
Q

HPV 16 and 18 mainly responsible for epidermodysplasia verruciformis

A

False, this is HPV 5 and 8

21
Q

HPV 16 and 18 largely cause genital and cervical dysplasia and carcinoma

A

True

22
Q

What strain of HPV causes plantar wart

A

HPV1

23
Q

What strain of HPV causes verruca vulgaris

A

HPV2

24
Q

What strains of HPV cause verruca plans

A

3 and 10