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Pharmacy Pre-Registration 20/21 > Infections-side effects > Flashcards

Flashcards in Infections-side effects Deck (18)
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1
Q

Drugs that cause ototoxicity? (3)

A

1) Aminoglycosides e.g gentamicin, steptomycin etc
2) Glycopeptides e.g vancomycin, teicoplanin etc
3) Macrolides e.g erythromycin etc

2
Q

Drugs that cause renal impairment? (2)

A

1) Aminoglycosides

2) Glycopeptides

3
Q

Drugs that cause hepatic impairment? (7)

A

1) Macrolides
2) Flucloxacillin (cholestatic jaundice)
3) Co-amoxiclav (Cholestatic jaundice)
4) Nitrofurantoin (hepatitis)
5) Tetracylines (hepatotoxicity)
6) Clindamycin (jaundice)
7) Monoflaxacin (life-threatening hepatotoxicity)

4
Q

Drugs that cause tendon rupture?

A

Quinolones e.g ciproflaxacin, monoflaxacin etc

5
Q

Drugs that cause skin photo-sensitivity?

A

1) Tetracyclines

2) Quinolones

6
Q

Antibiotic that impairs driving?

A

Ciproflaxacin

7
Q

Antibiotic that can cause ‘red man syndrome’?

A

Vancomycin

8
Q

Antibiotics that are teratogenic? (3)

A

1) Trimethoprim, Co-trimazole
2) Aminoglycosides (ear damage)
3) Tetracylines (deposits in bones)

9
Q

Antibiotics that cause blood disorders? (2)

A

1) Trimethoprim, co-trimazole

2) Glycopeptides

10
Q

Drugs that cause esophageal irritation?

A

1) Tetracylines

2) Clindamycin

11
Q

Antibiotic that can cause a hypertensive crisis and why?

A

Linezolid- it is an MAOI

12
Q

Antibiotics that can cause CNS toxicity?

A

Penicillins

13
Q

Antibiotics that can cause visual disturbance? (2)

A

1) Tetracylines- STOP

2) Metronidazole (optic neuropathy-REPORT)

14
Q

Antibiotics that prolong the QT interval? (2)

A

1) Quinolones

2) Macrolides

15
Q

CYP450 inhibitors?

A

Macrolides e.g erythromycin, clarithromycin etc

16
Q

CYP450 substrate?

A

Metronidazole

17
Q

Antibiotics that cause hyperkalaemia?

A

Trimethoprim, Co-trimazole

18
Q

Antbiotic that can cause pulmonary reactions?

A

Nitrofurantoin (look out for difficulty breathing)

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