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Flashcards in Immunophysiology Deck (163)
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61

Which part of the antibody binds to the antigen binding domain?

The aminoterminal end

62

Which part of the antibody binds to the surface receptors of cells

Effector region

63

Immunoglobulins can be cleaved by enzymes into...

  • Antigen binding fragments
  • Crystallisable Fragments

64

1: Monovalent

2: Bivalent

65

Which part of the antibody is in the red box?

FAB

(Fragment antigen binding)

66

Which part of the antibody is in the red box?

FC

Fraction crystallisable

(responsible for biological effect)

67

Which part of the antibody is in the red box?

2 x Hypervariable antigen binding sites

Each binds one antigen

68

Which part of the antibody is in the red box?

Joint region ('hinge')

Allow flexibility during binding

69

Variability in antibody class is known as...

Isotipia

70

Variability in individual antibodies is known as...

Allotipia

71

Variability in antibody Type is known as...

Idiotipia

72

Idiotype is determined by which region?

Variable region

73

Isotype is determined by which region?

Constant region

74

What forms antibodies?

Immunoglobin domains

75

Immunoglobulin domain

Loops form in the peptide chain

Caused by disulphide bonds

76

Complimentary Determining Region (CDR)

77

kappa

lambda

78

Mu

79

Gamma 1-4

80

Alpha 1-2

81

Delta

82

Epsilon

83

Neutrophil

Macrophage

84

Basophil

Mast cell

85

IgA dimer produced

Secreted into interstitial fluid

86

IgA binds to polymeric receptor

Contains secretory component

87

Secretory vesicle

Secretory IgA seperates

88

Secretory IgA binds to pathogen

89

Secretory-IgA

90

Pentamer IgM