Immunology Flashcards Preview

CMBM E3 CB > Immunology > Flashcards

Flashcards in Immunology Deck (5)
Loading flashcards...
1

What is primary lymphoid tissue?

Where stem cells differentiate into either T cells (thymus) or B cells (bone marrow).

2

What is secondary lymphoid tissue?

Where mature T/B cells go to encounter antigens.

3

Where is secondary lymphoid tissue in the body?

Lymph nodes
Spleen
MALT (mucosal-associated lymphoid tissue) and other locations in the body with excess lymphatic accumulations

4

What three activities take place in the thymus?

1. Differentiation of thymocytes into T cells: early thymocytes express antigen receptors
2. Self/non-self discrimination
3. Elimination of self-reacting thymocytes

5

What is involved in differentiation of thymocytes?

1. Cell-to-cell contact with cortical epithelial cells and dendritic cells
2. Thymic hormones
3. Cytokines