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Flashcards in Immuno notes Deck (11)
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1

How to MHC class I and II cells differ in their presentation of antigen?

MHC class I: have heavy chain and beta 2 microglobulin, antigen are processed in the cytoplasm
MHC class II: alpha and beta polypeptide chains, antigens are phagocytosed and digested by lysosomes within which antigens bind to MHC class II

2

only lymphocyte member of the innate immune system

natural killer cells

3

what vitamin do granulomas secrete?

vitamin D

4

recurrent bacterial infections and giardiasis

X linked brutons agammaglobulinemia

5

disseminated mycobacterial infections

IL-12 receptor deficiency

6

retained teeth, coarse facies, noninflamed staph abscesses

Hyper-IgE syndrome, Th1 fails to produce IFN-y

7

recurrent candida infections

chronic mucocutaneous candidiasis: t cell dysfunction

8

false positive BHCG tests due to presence of heterophile antibody

Selective IgA deficiency

9

poor smooth pursuit with eyes and recurrent infections

ataxia telangiectasia

10

CD18

LFA-1 integrin, seen in leukocyte adhesion deficiency

11

What is BTK?

found defective in brutons agammaglobulinemia = tyrosine kinase