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NBCE Part 1 > Immunity Review > Flashcards

Flashcards in Immunity Review Deck (4)
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1
Q

Describe the complement system (OILCAN)

A

Opsonization:
-opsonins bind to surface of bacteria marking them
-phagocytic cells bind to receptors increasing binding of opsonins
-C3b and C4b
Inflammation: mast cells in anaphylaxis (C3a, C4a, C5a)
Lysis: due to formation of MAC (C5b6789)
Chemotaxis: (C5a)
Agglutination: changes surface of bacteria making them sticky
Neutralization

2
Q

Describe B lymphocytes

A

involved in humoral immunity
Bone marrow
aka plasma cells
make antibodies in the form of immunoglobulins

3
Q

Describe T lymphocytes

A

95% of circulating lymphocytes
thymus
Cell-mediated immunity

4
Q

Describe differentiation of T cells

A

Precursors in bone marrow go to the thymus where they differentiate into CD8 or CD4