Flashcards in Immunity Review Deck (4)
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1
Q
Describe the complement system (OILCAN)
A
Opsonization:
-opsonins bind to surface of bacteria marking them
-phagocytic cells bind to receptors increasing binding of opsonins
-C3b and C4b
Inflammation: mast cells in anaphylaxis (C3a, C4a, C5a)
Lysis: due to formation of MAC (C5b6789)
Chemotaxis: (C5a)
Agglutination: changes surface of bacteria making them sticky
Neutralization
2
Q
Describe B lymphocytes
A
involved in humoral immunity
Bone marrow
aka plasma cells
make antibodies in the form of immunoglobulins
3
Q
Describe T lymphocytes
A
95% of circulating lymphocytes
thymus
Cell-mediated immunity
4
Q
Describe differentiation of T cells
A
Precursors in bone marrow go to the thymus where they differentiate into CD8 or CD4