How to treat cancer Flashcards

1
Q

What are oncologists

A

People who treat cancer without surgery

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2
Q

whats the difference between clinical oncologists and medical oncologists

A

clinical oncologists treat cancer with chemo and medical treat with drugs

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3
Q

radical treatment

A

treatment with curative intent

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4
Q

palliative treatment

A

treatment without curate intent to minimise side effects

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5
Q

adjuvant

A

after surgery to reduce risk of recurrence

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6
Q

non-adjuvant

A

attempt to shrink the tumour before surgical removal;

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7
Q

what are the 4 endpoints of cancer treatment

A

overall survival,
disease free survival,
progression free survival,
local control

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8
Q

overal survival

A

time alive

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9
Q

disease free survival

A

time alive without disease

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10
Q

progression free survival

A

time living where cancer is not getting worse

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11
Q

local control

A

time without recurrence or progression at specific site

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12
Q

cytotoxic chemotherapy kills what kind of cells

A

rapidly dividing ones

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13
Q

name the different types of cytotoxic chemotherapy

A
alkylating agents, 
platinum salts, 
anti-metabolites, 
taxanes, 
anthracyclines, topoisomerase inhibitors
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14
Q

side effects of chemo

A
malaise, fatigue
alopecia
GI - diarrhoea, ulcers, altered taste
low platelets
peripheral neuropathy
renal/ liver impairment
etc
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15
Q

radiotherapy side effects

A

affects targeted area

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16
Q

moa of radiotherapy

A

interacts with DNA causing double strand to break

17
Q

dose of radiotherapy is in

A

grays

18
Q

how many fractions over how long is radical radiotherapy

A

25-30 fractions over 4-6 weeks

19
Q

her2 targeting drugs used to treat

A

breast cancer

20
Q

what is the target from decision to treat to first treatment

A

31 days