Histopathology 2: Neoplastic Bone Disorders Flashcards Preview

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Flashcards in Histopathology 2: Neoplastic Bone Disorders Deck (12)
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1
Q

X-ray: Codman’s Triangle at end of long bones
Histology: Malignant mesenchymal cells

Diagnosis?

A

Osteosarcoma

2
Q

X-ray: Lytic lesions with fluffy calcification
Histology: Malignant chondrocytes

Diagnosis?

A

Chondrosarcoma

3
Q

X-ray: Onion skinning of periosteum
Histology: Sheets of small round cells
Karyotype: shows t(11;22)

Diagnosis ?

A

Ewing’s sarcoma

4
Q

X-ray: Lytic appearance in the epiphysis of knee
Histology: Giant cells look like osteoclasts, spindle/ovoid cells

Diagnosis?

A

Giant cell tumour

5
Q

X-ray: Soap bubble osteolysis, Shepherd’s crook deformity
Histology: Chinese letters

Diagnosis ?
Associated syndrome ?

A

Fibrocystic dysplasia

Albright syndrome

6
Q

List the triad of features Albright syndrome?

A
  • Polyostotic dysplasia
  • cafe au lait spots
  • Precocious puberty
7
Q

X-ray: Mushroom protuberance from Bone
Histology: Cartilage capped bony outgrowth

Diagnosis?

A

Osteochondroma

8
Q

X-ray: popcorn calcification
Histology: Proliferation of cartilage

Diagnosis ?

A

Enchondroma

9
Q

X-ray: Bulls eye appearance of radioleucent nidus with sclerotic rim
Histology: normal bone arising from osteoblasts

Diagnosis ?

A

Osteoid Osteoma

10
Q

Which benign bone tumour causes pain at night which is relieved by Aspirin ?

A

Osteoid osteoma

11
Q

In which syndrome do you get Osteomas, GI polyps and epidermoid cysts ?

A

Gardner syndrome

12
Q

Which bone tumour shows speckles mineralisation and is similar to osteoid osteoma ?

A

Osteoblastoma

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