Histology - GI Development Flashcards Preview

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Flashcards in Histology - GI Development Deck (32)
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1
Q

Liver, Gall Blader, and ventral part of pancreas derived from

A

Ventral Bud

1
Q

Omphalocele

A

no umbilical hernia reduction, mass may include foregut structures, high rate of mortality

2
Q

RA high Caudally

A

RA Concentration Gradient

2
Q

Hypertrophic pyloric stenosis

A

Smooth muscle hypertrophy/hyperplasia

3
Q

ilial diverticulum. ~2% of population, ~2 inches long, ~2 feet from ileocecal junction

A

2X2X2 rule

4
Q

270 degree purpose

A

Places small intestin within loop of large intestine

6
Q

not gut tube. From Visceral Mesoderm, intraperitoneal.

A

Spleen derivation

7
Q

Biliary duct atresia

A

Failure of duct to recanalize. Intrahepatic: generally fatal, Extrahepatic: often correctable

7
Q

Annular pancreas

A

Ventral bud encircles the duodenum. May constrict/occlude duodenum.

7
Q

Colorectoanal atresia

A

imperforate anus

9
Q

rectum & proximal anus

A

Anorectal canal

10
Q

Midgut developmental events

A

Week 5 - Week 12. Physiological umbilical herniation, 270 degree counterclockwise rotation, differential growth

11
Q

Pancrease source

A

Dorsal Pancreatic Bud

13
Q

prolifertation of epithelium that closes the lumen. Completes by week 5

A

Occlusion

14
Q

SHH & HOX

A

Concentric layering of the gut tube

15
Q

Distal anus derived from

A

ectoderm, separated by pectinate line

16
Q

malrotation

A

Left-sided colon, reverse intestinal rotation

17
Q

90 CCW rotation only

A

Left-sided colon

18
Q

greater omentum

A

Dorsal mesogastrium - bloody supply

18
Q

Physiological umbilical herniation purpose

A

Accomodates expanding liver & gut tube

19
Q

Reversed intestinal rotation

A

90 CCW, 180 CW - places large colonbehind duodenum.

20
Q

Jejunal, ileal stenoses/atresia

A

Ischemic necrosis, herniation, volvulus (twisting)

21
Q

Connects intestinal loop to yolk sac

A

Vitelline duct

22
Q

Growth induced reopening of the lumen - completes by week 9

A

Recanalization

24
Q

hindgut fistulas

A

Rectoperineal fistula, Colovaginal (rectovaginal) fistula, Colovesical (urorectal) fistula

25
Q

falciform ligament & lesser omentum

A

Ventral mesogastrium - liver budding, ends at umbilicus

26
Q

RA & HOX

A

Cephalocaudal differentiation

27
Q

SHH High in Lumen

A

SHH Concentration Gradient

28
Q

Remnant of vitelline duct, generally asymptomatic, but may present like appendicitis.

A

ileal (Meckel’s) diverticulum

30
Q

Urorectal septum forms

A

dividing cloaca into anorectal canal and urogenital sinus.

31
Q

Esophageal, gastric, duodenal stenoses/atresias

A

Improper recanalization - epithelial issue

32
Q

hernia due to anterior body wall defect, mass not within umbilicus, lower mortality

A

Gastroschisis