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Year 3: Gastro > hepatocellular carcinoma? > Flashcards

Flashcards in hepatocellular carcinoma? Deck (7)
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1
Q

define hepatocellular carcinoma?

A

● Primary malignancy of the liver parenchyma

2
Q

what is the main risk factor for hepatocellular carcinoma?

A

cirrhosis

3
Q

what are the most common causes of hepatocellular carcinoma?

A

● Hepatitis B- most common cause world wide

● Hepatitis C – most common cause in Europe

4
Q

what is the epidemiology of hepatocellular carcinoma?

A

● Third most common cause of cancer worldwide

● LESS common than liver metastases

5
Q

what are the presenting symptoms of hepatocellular carcinoma?

A
o	Abdominal distension
o	jaundice
o	ascites 
o	RUQ pain  
o	Hepatomegaly 
o	Pruritis 
o	Splenomegaly 
o	Constitutional symptoms
o	History of Exposure to Carcinogens
6
Q

first line investigations for hepatocellular carcinoma?

A

o AFP and abdominal USS

7
Q

what is the gold standard investigation for staging?

A

o CT/MRI