Hemostasis Defects Flashcards Preview

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Flashcards in Hemostasis Defects Deck (66)
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61

What test is prolonged in lupus anticoagulant?

Prolongs the PTT

62

What are some symptoms of lupus anticoagulant?

Deep vein throbosis, pulmonary embolism, thrombotic strokes and recurrent miscarriage due to thrombotic disease of the placental blood

63

Is PTT corrected when normal plasma is mixed with the plasma from a patient with lupus anticoagulant?

no

64

What are the most common familial congenital condition which cause hypercoagulable syndromes?

Deficiencies of
-antithrombin (AD)
-protein C (AD)
-protein S (AD)
-resistance to protein C (Factor V Leiden)

65

What are the symptoms of someone who has homozygous deficiencies in either protein C or S?

Heterozygous

Fetal at birth

Presents after puberty with recurrent venous thrombotic disease

66

Mutation in Factor V causes it not to inactivated by ________.

Which patient population are heterozygous states common?

Protein C

Europeans