Hemostasis Defects Flashcards

1
Q

What test will be abnormal in Dysfibrinogenemia?

A

TCT

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2
Q

What test will be abnormal in Hypofibrinogenemia?

A

fibrinogen

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3
Q

What test will be abnormal in Thrombocytopenia?

A

platelet count

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4
Q

What test will be abnormal in Platelet dysfunction?

A

bleeding time

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5
Q

What test will be abnormal in Hemophilia?

A

PTT

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6
Q

What test will be abnormal in Factor VII deficiency?

A

PT/INR

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7
Q

______ can be diagnosed using the platelet count test.

A

Thrombocytopenia

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8
Q

______ can be diagnosed using the bleeding time test.

A

Platelet dysfunction

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9
Q

_____ can be diagnosed via an abnormal PTT test.

A

Hemophilia

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10
Q

_____ can be diagnosed by an abnormal PT/INR test.

A

factor VII deficiency

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11
Q

______ can be diagnosed using the TCT test.

A

Dysfibrinogenemia

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12
Q

_____ can be diagnosed using the fibrinogen test.

A

Hypofibrinogenemia

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13
Q

What is lupus anticoagulant associated with?

A

thrombosis

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14
Q

What is pancytopenia?

A

low RBCs, WBCs, and platelets

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15
Q

If you see mucocutaneous bleeding, think ____. If you see soft tissue, joint, or deep bleeding, think ____.

A

platelet or vWF defect; coagulpathy

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16
Q

If the Epi PFA test is abnormal but the ADP PFA test is normal, think ____.

A

aspirin effect

17
Q

If the Epi PFA test is abnormal AND the ADP PFA test is ALSO abnormal, think ____.

A

abnormal platelet function (uremia, low platelet count, Hct low)

18
Q

What is the TT?

A

thrombin time- measures the procoagulant activity of

fibrinogen and is also very sensitive to the anticoagulant effect of heparin or fibrin split products

19
Q

What is the BT?

A

bleeding time- measures the platelet and vessel interaction, as well as the number and the function of platelets- not really used anymore but would show low platelet count or vWD

20
Q

What is the PFA?

A

platelet function analyzer- measures in vivo bleeding time

21
Q

What is the most common presentation of factor XI deficiency?

A

post-op bleeding

22
Q

What is ristocetin-induced-platelet-aggregation?

A

a test for vWD to check abnormal platelet aggregations

23
Q

What will abnormal factor VIII inhibitor look like?

A

abnormal PTT, mixing test that doesn’t correct

24
Q

What findings will be seen in DIC lab tests?

A
Prolonged PT
Greatly prolonged PTT
Prolonged thrombin time
Low platelet count
Low fibrinogen level
Increased fibrin split products
Increased D-dimer
25
Q

How is lupus anticoagulant found?

A

abnormal PTT that does not correct; thrombotic syndrome; abnormal dilute Russell’s Viper Venom Test (dRVVT)