Heme Morphology quiz Flashcards Preview

Med Lab Tech Fall 2016 > Heme Morphology quiz > Flashcards

Flashcards in Heme Morphology quiz Deck (72)
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1

Name this cell

 

Sézary cell

2

What is this red cell inclusion indicative of?

Basophilic stippling is indicative of lead poisoning

3

Name the leukemia and subgroup

What's another name for this subgroup?

  • Relatively uncommon
  • Characterized by a neoplastic proliferation of megakaryoblasts

Acute myelocytic leukemia M7

4

What type of non-malignant leukocyte disorder is represented in this smear?

  • Deeply stained
  • coarse azurophilic granules
  • rich in myeloperoxidase
  • changes are transient
  • frequently associated with severe infection

Toxic granulation

5

Name the anomaly

  • Autosomal-dominant
  • hyposegmentation

Pelger-Huët anomaly

6

Granulocytic WBCs

What WBCs are labeled A?

What WBCs are labeled B?

What WBCs are labeled C?

A: Neutrophilic metamyelocytes

B: Neutrophilic bands

C: Segmented neutrophils

7

Name the WBC:

Monocyte

 

8

Name this leukemia

  • Panmyelosis
  • 20% of all leukemias in adults
  • Clonal myeloid stem cell disorder
  • Slight male predominance
  • Found mostly in individuals 45-55y.o
  • Unusual in Children
  • Extramedullary myelopoiesis
  • Splenomegaly

Chronic mylogenous leukemia

9

Identify the anemia

  • Hypocellular bone marrow with adipose cells

Aplastic anemia

10

Name this leukemia and subgroup

  • Large cells typically
  • Irregular; clefted/indented nucleus
  • Heterogeneous chromatin pattern
  • Low N:C ratio
  • Prominent nucleolus
  • Abundant cytoplasm
  • Resembles M1

Acute lymphocytic leukemia L2

11

What erythroid cell is the aroow referring to?

Rubriblast

12

Name the cell the arrow is pointing to (red cell lineage)

Prorubricyte

13

Name the leukemia and subgroup

  • Primitive leukemic blasts w/ no distinct myeloid morphological features
  • Lack reactivity w/ conventional cytochemical stains
  • Prognosis poor

Acute myelocytic leukemia M0

14

Name this stain

What is it used for?

Periodic Acid Schiff stain

Aids in diagnosis of AML M6

15

Name this stain

What does it stain?

What does it differentiate?

Myeloperoxidase stain

It stains the primary granules of myeloid cells

It differentiates AML from ALL

16

Name the N/N anemia:

  • mild to moderate macrocytic anemia with prominent anisocytosis and poikilocytosis
  • autosomal recessive
  • bone marroe erythroblasts show megaloblastic maturation
  • 1-3% of marrow erythroblasts are binucleated or contain chromatin bridges

Congenital Dyserythropoietic Anemia Type I

17

Name this red blood cell abnormality:

3-12 UNEVEN spicules

Acanthocytes

18

Name the immature granulocytic WBC in the center:

Myeloblast

19

What disorder is the following:

  • Ineffective erythropoiesis

Decreased:

  • Hgb and Hct
    • causing microcytic/hypochromic cells
  • MCV
  • MCH
  • Serum Fe
  • % saturation
  • Ferritin

Increased:

  • RDW- only slightly
  • Retics
  • TIBC- normal to increased
  • FEP

Iron defiiency anemia

20

What type of WBC is A?

Neutrophilic myelocyte

21

What is the arrow pointing to?

Auer rod

22

What inclusion are the arrows pointing to?

  • Grey-blue inclusions in the cytoplasm
  • spindle-shaped
  • aggregated strands of rough ER
  • transient

Döhle bodies

23

What is the inclusion?

What is it associated with?

  • Denatured hemoglobin
  • crystal violet/ brilliant cresyl blue stain

 

Heinz bodies

associated with G-6-PD deficiency

24

What type of non-malignant leukocyte disorder is present in this stain?

  • suggests the presence of infection or severe inflammation
  • qualitative change in neutrophilia

Toxic vacuoles

25

Name the WBC

Hypersegmented neutrophils

26

What type of WBCs are A?

What type are B?

A: Prolymphocytes

B: Lymphocytes

27

  1. What type of N/N anemia does this represent?
  2. What is another name for this anemia?
  3. What test tells you the identity of this anemia?
  • Mild to severe normocytic anemia
  • 10-50% of erythroblasts in the marrow are binucleated or multinucleated
  • Autosomal recessive
  • Most commonly seen form in its "group"
  • Reacts with anti-i

  1. Congenital dyserythropoietic anemia Type II
  2. HEMPAS- hereditary erythroblasts multinuclearity with a positive acid serum test
  3. HAM's test

28

Name the WBC that the left-most arrow is pointing to.

What are 2 alternative names for this type of cell?

Reactive lymphocyte

AKA Turk cells or Downey cells

29

Name the RBC morphology

What are some disease states that may cause this?

  • 10-30 rounded spicules evenly placed over the surface of the RBC
  • Associated with uremia

Echinocytes

Causes:

  • heart disease,
  • bleeding ulcers,
  • cancer of the stomach,
  • severe burns,
  • renal disease,
  • liver disease

30

Name the cell

What stain is positive for this cell?

Hairy Cell leukemia

TRAP stain