Hematology Lab Final Flashcards Preview

Med Lab Tech Fall 2016 > Hematology Lab Final > Flashcards

Flashcards in Hematology Lab Final Deck (94)
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1

The purpose of ______ ________ is to detect a lab error that may result in a clinical error.

Quality control

2

___________________ identifies several major activities of importance to a laboratory quality program.

Clinical Laboratory Standards Institute (CLSI)

3

What are the three step for clotting?

1. Constrict the blood vessel in the region of the hole

2. Form a platelet plug

3. Seal the plug with fibrin

4

Specimen factors affecting coagulation testing (6)

  • Collection system
    • Order of draw
  • Anticoagulant
  • Phlebotomy technique
  • Centrifugation
  • Delays in handling
  • Storage conditions

5

Specimen factors affecting coagulation testing falls under:

A. analytical

B. Preanalytical

C. Preanalytical and analytical

C. Preanalytical and analytical

6

Instrument factors affecting coagulation testing include (6)

  • Temperature
  • Light sensor
  • Detector
  • Timer
  • Disposables
  • Reagent Delivery

7

Instrument factors affecting coagulation testing fall under:

A. analytical

B. Preanalytical and analytical

C. Preanalytical

A. analytical

8

Reagents and Control factors affecting coagulation testing include (6)

  • Shipping conditions
  • Storage conditions
  • Reconstitution
  • Contamination
  • Deterioration
  • Lot changes

9

Reagent and control factors affecting coagulation testing are a part of:

A. Analytical

B. Preanalytical

C. Preanalytical and Analytical

A. Analytical

10

What is the purpose of Internal Quality Control?

To assess ongoing assay performance to ensure assays are:

  • performing according to specifications
  • results are accurate and reliable
  • ensure reproducibility of testing

11

What is External Quality Assurance?

Peer group assessment process that allows a laboratory to assess individual analytes against those of other laboratories using either the same or different reagents or instrumentation.

12

What is the anticoagulant used in coagulation studies?

Sodium citrate

13

What is the ratio of blood to anticoagulant?

9:1

14

Clot based methodologies are usually performed at what temperature?

37C +/- 1

15

Freeze plasma at ______ is unable to perform testing within 4 hours

-70C

16

Freeze plasma at -70C if unable to perform testing within ____ hours

4 hours

17

A fibrometer is an example of:

a. Mechanical endpoint detection

b. Photo-optical endpoint detection

c. Chromogenic endpoint detection

d. Immunogenic endpoint detection

a. Mechanical endpoint detection

18

Diagnostica Stago STAanalyzers and the Trinity Biotech Destiny line are examples of:

a. Mechanical endpoint detection

b. Photo-optical endpoint detection

c. Chromogenic endpoint detection

d. Immunogenic endpoint detection

a. Mechanical endpoint detection

19

Photo-Optical endpoint detection is also known as what?

Turbidometric methodology

20

This is the most common method of detection utilized on coagulation instruments

Photo-Optical endpoint detection

21

What is also known as amidolytic methodology?

Chromogenic endpoint detection

22

This endpoint detection system is based on the attachment of pNA to a synthetic chromogenic substrate

Chromogenic endpoint detection

23

This type of endpoint detection is based on antibody-antigen reactions

Immunogenic endpoint detection

24

Definition:

the time taken for a standardized skin incision to stop bleeding

Bleeding Time (BT)

25

On vessel injury, platelets adhere to _________ exposed in the subendothelium with assistance from _____________ and form a homeostatic platelet plus.

collagen, von Willebrand Factor

26

What does bleeding time measure?

Platelet number and function

27

Which bleeding time method makes a standardized puncture of the ear lobe?

Duke Method

28

In this bleeding time method a blood pressure cuff is used to maintain constant pressure within the capillaries to help standardize the procedure, the forearm is the site of incision, and a sterile/disposable lancet is used.

Ivy Method

29

This bleeding time method uses a Bard-Parker or similar disposable blade

Mielke Method

30

This bleeding time method uses a spring activated device

Simplate/Surgicutte Method