Hematology Flashcards

0
Q

What is the most common microcytic anemia?

A

Iron deficiency anemia

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1
Q

What is the normal range for MCV?

A

80-100

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2
Q

What two main causes should you be thinking of in a macrocytic anemia?

A

Malnutrition and severe blood loss

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3
Q

Auer rods are most commonly associated with what disease?

A

Acute myeloid leukemia

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4
Q

What molecule binds iron in the bloodstream?

A

Transferrin

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5
Q

What does koilonychia refer to?

A

Spoon shaped nails. This may be found in microcytic anemia.

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6
Q

A low retic count and a normal serum ferritin should make you think of what diagnosis?

A

Anemia of chronic disease

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7
Q

Under normal conditions at what hemoglobin level would you began to consider a transfusion?

A

8

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8
Q

Which anemia should you think of if you see the term Howell-Jolly bodies?

A

Sickle cell due to functional asplenia, but it may also show up in folic acid deficiency.

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9
Q

G6PD deficiency follows what pattern of inheritance?

A

X-linked

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10
Q

List the three diagnosis you should be thinking of if a question includes Heinz bodies?

A

G6PD deficiency anemia, chronic liver disease, alpha thalassemia

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11
Q

Are target cells seen in mild or severe iron deficiency anemia?

A

Severe, they are also seen in alpha thalassemia, chronic liver disease and asplenia.

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12
Q

Iron deficiency anemia will have a serum iron lower than what value?

A

30

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13
Q

You should be thinking alpha thalassemia if the question stem includes which four geographic areas?

A

Southeast Asia, China, Middle East, Africa

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14
Q

A patient of Mediterranean descent is a clue for which type of anemia?

A

Beta thalassemia

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15
Q

In a folic acid deficiency anemia the folic acid level is typically below what level?

A

<150

16
Q

The term Philadelphia chromosome should make you think of what diagnosis?

A

Chronic myeloid leukemia

17
Q

WBC

A

4-11 (Medscape)

18
Q

Hb

A

14-17.5 men

12.3-15.3 women (Medscape)

19
Q

Hct

A

40-54% men

36-46% women (Medscape)

20
Q

Platelets

A

150,000-450,000 (Hopkins)

21
Q

Thalassemias

A

Microcytosis, target cells
A2 or F in beta-thalassemia
Electrophoresis

22
Q

Multiple myeloma

A

Bone pain, fx & hypercalcemia MC findings

Bence-Jones proteins

23
Q

Schilling test was to?

A

Determine the cause of B12 deficiency

24
Q

Reed-Sternberg cells

A

Hodgkin Lymphoma
Painless lymphadenopathy
Peak 20s or >50
Most patients present w/ painless mass, commonly in neck

25
Q

Christmas disease

A

Hemophilia B (factor IX hemophilia)
Hereditary bleeding disorder.
Managed w/ factor IX concentrates or FFP

26
Q

Heparin-induced thrombocytopenia

A

Thrombosis occurs in 50% of cases;

Bleeding is uncommon

27
Q

Is sickle cell microcytic, macrocytic or normocytic?

A

Microcytic

28
Q

List four disease states in which you may find basophilic stippling.

A

Lead poisoning, Beta or alpha thalassemia, sideroblastic anemia, arsenic poisoning.