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Stage 3 Human Diseases > HD4: Virology > Flashcards

Flashcards in HD4: Virology Deck (38)
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1

How many genes does a virus encode for?
2) What are the 2 main things they encode for?

3-100
2) structural proteins (to form part of a new virus) and non-structural proteins (e.g. enzymes)

2

What are the 2 roles of non-structural protein genes virus' can encode for?

Act with cellular enzymes to replicate virus
May switch of host cell activities / block immune system

3

What are the 2 shapes capsids come in?
2) Do they attach to host cells?

sphere or icosohedron.
2) yes if lipid envelope is not present

4

Why can't virus be classified based on disease?

different virus ause the same symptom disease, same virus cause different disease or none at all normally

5

classify the virus:
Herpes viruses (HSV, cold sores, chickenpox  varicella zoster)

double stranded DNA virus

6

classify the virus:
Hepatitis B virus

double stranded DNA virus

7

classify the virus:
adenovirus

double stranded DNA virus

8

classify the virus:
influenza virus

singles stranded RNA virus

9

classify the virus:
measles

singles stranded RNA virus

10

classify the virus:
HIV

retrovirus, are an RNA virus, but not as have a reverse transcription stage

11

classify the virus:
parvovirus (childhood rash illness)

single-stranded DNA

12

classify the virus:
rotavirus (childhood diarrhoea

double-stranded RNA

13

classify the virus:
Mumps

singles stranded RNA virus

14

classify the virus:
Rhinovirus

singles stranded RNA virus

15

classify the virus:
Hepatitis C virus

singles stranded RNA virus

16

What are the oral manifestations of herpangina?
2) What type of virus is it?

1) common lesions in the mouth , ulcers on palate
2) enterovirus (positive sense single stranded RNA)

17

What are the oral manifestations of oral hairy leucoplakia
2) what is its other name?
3) who will be affected by it?

1) white patch on tongue that doesn't rub of
2) epstein barr virus
3) immunocomprimised patients

18

What does a herpes simplex virus look like under electron microscope?

fried egg, the yolk is the capsid, the white is the lipid envelope

19

What does the measles virus look like under an electron microscope?

a sack= lipid envelope, with rectanglke stringy stuff (capid, which is coating RNA)

20

What is the difference between the capsids of measles and herpes simplex virus?

herpes simplex, spherical (contains DNA)
while measles is rectangley shape (and is coating RNA)

21

What is the name of the virus where the capsid is icosahedral and there are surface proteins?

adenovirus

22

What is the name of the virus where the capsid is ovally shape with a thin lipid envelope that is lineated (the lines are caused by presence of surface proteins. It is a flourescent green image

infleunza virus

23

What is the viral intracellular life cycle: (5)

Attachment
B entry
C replication and protein synthesis
D assembly
Release

24

In which groups will viral infections be more severe?

compromised
extremes of age
preganancy (infections may affect foetus)

25

TRUE OR FALSE
If someone has acute hep B and are symptomatic, this shows the immune system is
fighting off the infection.

TRUE

26

acute, persistent, reactivation or latent
Categorise:
measles

acute

27

acute, persistent, reactivation or latent
Categorise:
adenovirus

persistent

28

acute, persistent, reactivation or latent
Categorise:
herpesvirus family

latent

29

acute, persistent, reactivation or latent
Categorise:
cold sores and shingles

reactivation

30

acute, persistent, reactivation or latent
Categorise:
mumps

acute