HD3: Natural history of infection Flashcards Preview

Stage 3 Human Diseases > HD3: Natural history of infection > Flashcards

Flashcards in HD3: Natural history of infection Deck (75)
Loading flashcards...
31

Protozoa
a) single or multicellular?
b) motile or no?

a)Single cell organisms
b) Very motile

32

Can protozoa encyst?

yes

33

Protozoa, true or false
can engulf food

c)True: Can engulf food

34

Protozoa, true or false
won't survive hostile intracellular

d) False: Often survive hostile intracellular environmen

35

Protozoa
method of reproduction?

e)Asexual and sexual reproduction

36

Parasites
a) single or multicellular?

complex multicellular

37

PARASITE
DESCRIBE RELA. WITH HOST

symbiotic

38

Parasites often have a life cycle outside of host
true or false

true

39

What are the 2 ways parasites cause disease?

Direct tissue damage
- Immunological reaction to parasite.

40

Which host defence method is missing:
1) skin and membranes with commensal bacteria
2) complement- help fight bacterial infections
3) phagocytois by neutrophils and macrophages
4) cytokines
5) innate immunity and humoral immunity

secretions

41

Which host defence method is missing:
1) skin and membranes with commensal bacteria
2) secretions
3) phagocytois by neutrophils and macrophages
4) cytokines
5) innate immunity and humoral immunity

complement- help fight bacterial infections

42

Which host defence method is missing:
1) complement- help fight bacterial infections
2) secretions
3) phagocytois by neutrophils and macrophages
4) cytokines
5) innate immunity and humoral immunity

skin and membranes with commensal bacteria

43

Which host defence method is missing:
1) complement- help fight bacterial infections
2) secretions
3) skin and membranes with commensal bacteria
4) cytokines
5) innate immunity and humoral immunity

phagocytois by neutrophils and macrophages

44

Which host defence method is missing:
1) complement- help fight bacterial infections
2) phagocytois by neutrophils and macrophages
3) skin and membranes with commensal bacteria
4) secretions
5) innate immunity and humoral immunity

cytokines

45

what is the difference between cell-mediated and humoral immunity?

Humoral immunity secretes antibodies to fight against antigens, whereas cell-mediated immunity secretes cytokines and no antibodies to attack the pathogens.

46

What is the innate immune response comprise of?

the basic bitches, the ones at the front of the que. These mechanisms include physical barriers such as skin, chemicals in the blood, and immune system cells that attack foreign cells in the body.

47

What are the innate immune system cells?

Natural killer cells, mast cells, eosinophils, basophils; and the phagocytic cells include macrophages, neutrophils, and dendritic cells,

48

what happens after a non-specific innate immune response?

the adaptive immune repsonse

49

Which immunoglobulin is involved in the innate immune response?

IgA

50

Is this part of the innate or adaptive immune response:
Recruitment of cells of innate immune cells through cytokines (such as histamine,
prostoglandins e.t.c)

innate

51

Is this part of the innate or adaptive immune response:
Complement- opsinisation, chemoattraction direct effect against Bacteria

innate

52

Is this part of the innate or adaptive immune response:
Recognition of pathogens through antigen presentation

adaptive

53

Is this part of the innate or adaptive immune response:
Antigen presentation

innate

54

Is this part of the innate or adaptive immune response:
Specific activation of specialised cells

adaptive

55

Is this part of the innate or adaptive immune response:
Development of ‘memory’ to allow quick recognition of pathogen in future

adaptive

56

Which is the innate and whic is the adaptive immune response:
antigen presentation followed by the recognition of presented antigen leading to activation of specialised lymphocytes through

the antigen presentation is done by innate immune cells, (but can also be done by adaptive)
the recognition and activation part is the adaptive immune respone

57

What MHC class (the molecule of the antigen presenting cell or infected target cell that holds the presented antigen) does the folllowing interact with and thus cause activation of:
a) CD4+ T cells
b) CD8+ T cells

a) MHC class 2
b) MHC class 1

58

To present the antigen on an MHC class 2 molecule, how does the antigen presenting cell process the antigen?

exogenous pathway

59

To present the antigen on an MHC class 1 molecule, how does the antigen presenting cell process the antigen?

endogenous pathway

60

If an infected target cell e.g. a macrophage, is presenting an antigen on the MHC class 2 which will the result be:
b) What type of immunity is this?

1) activation of CH4+ T cell (Th1 cell)
2) release of cytokine: IFN-gamma
3) Enhanced opsonisation of bacteria/viruses (often intracellular) through B cell
antibody production.
b) cell-mediated immunity