Haloperiodol Flashcards Preview

Block 6 PHARMACOLOGY > Haloperiodol > Flashcards

Flashcards in Haloperiodol Deck (4)
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1
Q

what is haloperidol?

A

A dopamine receptor antagonist, a psychotropic agent

2
Q

what is haloperidol used to treat?

A

schizophrenia

3
Q

. Haloperidol’s mechanism of action is unknown. However it is thought to act via:

A

1) Depressing the CNS at the subcortical level of the brain, midbrain, and brain stem reticular formation, via inhibition of the ascending reticular activating system of the brain stem (possibly through the caudate nucleus), thereby interrupting the impulse between the diencephalon and the cortex.
2) Antagonizing the actions of glutamic acid within the extrapyramidal system,
3) Inhibiting catecholamine receptors
4) Inhibiting the reuptake of various neurotransmitters in the midbrain
5) Directly affect the chemoreceptor trigger zone (CTZ) through the blocking of dopamine receptors.

4
Q

why is haloperidol used to treat schizophrenia

A

with sedative and antiemetic activity