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Flashcards in Growing Deck (11)
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1

How do we measure growth?

-Weight
-Height/length
-Head circumference

2

What is the significance of growth charts

-A method of describing the growth of a normal population- the reference population
-A way of comparing the growth of an individual with the reference population
-A tool helping to define abnormal growth of an individual

3

How do we construct growth charts

-Define the reference population
-A mathematical construct
-Longitudinal or cross-section
-Centiles

4

What are the 3 phases of growth & their requirements?

1.) Infancy
-nutrition
-insulin
2.)Mid-childhood
-Growth hormone
-thyroxine
3.) Puberty
-GH
-sex hormone

5

Define anthropometry

The scientific study of the measurements and proportions of the human body.

6

What is Laron's syndrome

-May cause short stature
-GH insensitivity

7

What are some signs of coeliac disease

-Tiredness
-Anaemia
-Positive antibodies
-Positive jejunal biopsy
-Response to diet

8

List some first line investigations for abnormal growth

-FBC
-Ferritin
-U&E (kidney function)
-CRP/ESR
-TFT
-Coeliac screen
-IGF-1
-Bone age
-CGH array/karyotype

9

How do we obtain subischial leg length?

-Subtract sitting height from standing height

10

List some second line investigations for abnormal growth

-GH provocation test ( stress people to produce it) +/- additional pituitary function tests
-MRI brain
-Skeletal survey

11

Which conditions has treatment with GH been licensed for ?

-GH deficiency
-Turner's syndrome
-Prader Willi syndrome
-SHOX deficiency
-Chronic renal failure
-SGA& poor catch up