What is the MOA for Glucagon?
Increases blood glucose level by stimulating glycogenolysis mainly within the liver
What are the indications for Glucagon?
Hypoglycaemia when patient cannot swallow food/glucose gel and where IV access cannot be obtained
What are the contraindications and cautions for Glucagon?
Contra: Known severe allergy
Cautions: None
Can Glucagon be used in pregnancy or while breastfeeding?
Safe and should be administered if indicated
What doseage of Glucagon should be administered?
*1 mg IM for an adult or child aged five and over
*0.5mg IM < 5 years old
DO NOT REPEAT DOSE
What is the onset and duration of effect of Glucagon?
5-10 min onset, 15-60 min duration
What are the adverse effects of glucagon?
None
When might glucagon be ineffective in a hypoglycaemic patient?
If glycogen stores are depleted, it will not be effective.
e.g. strenuous exercise, has not eaten >12hrs, adrenal insufficiency, chronic hypoglycaemia, alcohol induced hypoglycaemia
What should you give a patient after giving glucagon?
If competent, you must give patient some food to replace depleted glycogen reserves