This antacid reacts rapidly with HCL
Sodium Bicarbonate
Side effects of Aluminum or Magnesium hydroxide
Aluminum - Constipation
Magnesium - Diarrhea
What antacid can lead to hypercalcemia, renal insufficiency and metabolic alkalosis
Calcium carbonate
What are the histamine blockers that go through first pass effect
Cimentidine
Ranitidine
Famotidine
Clinical use of H2 blocker
GERD
Peptic Ulcer disease
Non ulcer dyapepsia
Prevention of bleeding
AE of cimentidine
Mental status change
Gynecomastia
Galactorrhea
Impotence
Treatment of acid peptic disease
Proton Pump Inhibitors
When do you administers PPI o
On an empty stomach
MoA of PPI
Inhibit both acid fasting and meal stimulated secretion
AE of PPI
CAR infection
Nosocomial pneumonia
Enteric infection
What PPI may inhibit warfarin,diazepam and phenytoin
Omeprazole
This ppi enhances clearance of theophylline
Lansoprazole
Has limited solubility, breaking down into sucrose sulfate and aluminum salt
Sucralfate
Used for prevention of traveler’s diarrhea
Bismuth compounds
What is now used for acute large bowel distention or oglivie’s syndrome
Neostigmine
Potent anti nausea and anti emetic action
Dopamine antagonist
Metoclopromide
Domperidone
This drug has extrapyramidal effects
Metoclopromide
Bulk forming laxative
Psyllium
Methycellulose
Polycarbophil
AE of bulk forming stool
Bloating
Flatus
Stool softeners
Docusate
Glycerin suppository
Mineral oil
AE of stool softeners
Impair absorption of ADEK
Commonly used osmotic laxative
Magnesium hydroxide
Milk of magnesia
Sugars that prevent or treat chronic constipation
Sorbitol
Lactulose
Given before endoscopy
Balanced PEG
These drugs may decrease diarrhea by excess fecal bile acids
Colestyramine
Colestipol
Colesevelam
AE of somatostatin
Stearrothrea
Serotonin receptor antagonist activate afferwnt pain sensation
Alosetron
Used for severe IBS with predominant diarrhea
Alosetron
Given with severe ibs with predominant constipation
Tegaserod
What is the pathway used by antiemetic agents
Nucleus tractus solitarius
Clinical usage of serotonin antagonist
Chemotheraphy induced nausea and vomting
Post operative and radiation nausea and vomiting
This anti emetic drugs can cross the bbb
Neurokinin antagonist
Apreripant
Fosaprepitant
Antipsychotic drug that is potent antiemetic and sedative
Phenothiazines
Central dopaminergic blockade
Droperidol
Treatment of emesis due to chemotherapy
Diphenhydramine
Best agent used for the prevention of motion sickness
Hyoscine
Scopolamine
Drug used to reduced anticipatory vomiting by anxiety
Lorazepam
Diazepam
Mesalamine compounds
Rowasa or canasa (suppositories)
Given for crohn’s disease
Moderate to severe active inflammatory bowel disease
glucocorticoid
Budesonide
Severe crohn’s disease
Anti integrin therapy
Natalizumab