Gastric Phase of a Meal Flashcards Preview

Physiology > Gastric Phase of a Meal > Flashcards

Flashcards in Gastric Phase of a Meal Deck (74)
Loading flashcards...
1

What is often the cause of gastric ulcers?

Loss of the mucosal barrier

2

What is often NOT the cause of gastric ulcers?

Hypersecretion of acid

3

What is the function of H+ secretion in the stomach?

It kills microorganisms and it converts pepsinogen into pepsin

4

What is the function of intrinsic factor?

It is crucial for the absorption of Vitamin B12

5

What is a powerful paracrine stimulator of H+ secretion in the stomach?

Histamine

6

What is the strongest regulation of stomach function?

Neural regulation - both intrinsic and extrinsic

7

What are some hormones involved in the endocrine regulation of the stomach?

Gastrin
Somatostatin

8

What is the function of gastrin?

Stimulates gastric acid secretion

9

What is the function of somatostatin?

Inhibits gastric secretion

10

What is secreted in the stomach to protect against the acidity?

Mucus and HCO3-

11

When the stomach is not being emptied, what is the status of the pylorus?

Closed

12

What is the function of the distal stomach (antrum and pylorus)?

It is a thick muscular wall that is used for grinding and mixing the contents of the stomach

13

What is the function of the fundus and body of the stomach?

Reservoir and also provides a tonic force for emptying

14

What is the function of the cardia of the stomach?

Prevents esophageal reflux

15

What are the 3 regions of the stomach?

Cardia
Fundus/Body
Antrum

16

What is the orad stomach?

It is the proximal part closer to the mouth

17

What is the caudad stomach?

It is the distal part further away from the mouth

18

What are the gastric pits?

They are the openings where the gastric glands empty

19

What are the primary glands of the cardia?

Primarily mucus and HCO3- secreting gland cells, that provide mechanical and chemical protection of the gastric mucosa.

20

What are the primary glands of the fundus?

Oxyntic or parietal gland region

21

What are the primary glands of the antrum?

Pyloric gland region

22

What do parietal/oxyntic cells secrete?

HCl
Intrinsic Factor

23

What is the function of the HCl secreted by the parietal/oxyntic cells?

Kills bacteria, and allows activation of pepsin from pepsinogen, low pH for effective pepsin action.

24

What is the function of intrinsic factor secreted by the parietal/oxyntic cells?

It is an essential factor that allows for the absorption of Vitamin B12

25

What do mucus neck cells secrete?

Mucus

26

What is the function of mucus secreted by mucus neck cells?

Protects the gastric mucosa

27

What do peptic/chief cells secrete?

Pepsinogens, which become active as pepsins in acidic environments

28

What do enterochromaffin-like cells (ECL) secrete?

Histamine - the most powerful stimulant of HCl secretion

29

What do D cells secrete?

Somatostatin - most powerful inhibitor of HCl secretion

30

Where are G cells located?

Pyloric region

Decks in Physiology Class (81):