Gallbladder Flashcards Preview

Liver, biliary tree and gallbladder > Gallbladder > Flashcards

Flashcards in Gallbladder Deck (6)
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1
Q

This gene is associated with an increased risk for the development of cholesterol gallstones.

A

ABCG8 (ATP-binding cassette transporter)

2
Q

What type of stones are found in sterile gallbladder bile?

A
Pigment stones (black stones)
Remarks: Brown stones in infected large bile ducts
3
Q

Cholecystitis without gallstones account for how many percent of patients with cholecystitis?

A

10%

4
Q

State a cause of acalculous cholecystitis.

A

Any of the ff: 1. sepsis with hypotension and multisystem organ failure (ischemic conditions); 2. immunosuppression; 3. major trauma and burns; 4. diabetes mellitus; 5. infections.

5
Q

What percentage of patients with gallstones develop gallbladder cancer?

A

1 to 2%

6
Q

State three genes that are mutated in gallbladder cancer?

A

ERBB2 (Her2/neu) overexpression; PBRM1 and MLL3