Flashcards in Final Exam GI Physiology: Large Intestine Deck (9)
What are the 4 luminal secretions of the large intestine?
HCO3- (exchanged for Cl-)
H+ (exchanged for Na+)
K+ (in response to aldosterone)
What 2 paracrine substances does the large intestine secrete?
Histamine and prostaglandin (vasodilators)
What is the 1 endocrine substance secreted by the large intestine?
Na+ and Cl- are largely reabsorbed in the ___________ after having escaped reabsorption in the small intestine.
What 2 nerves are responsible for large intestine cholinergic and VIPergic stimulation?
Vagus n. and Pelvic n.
Does the large intestine have luminal membrane Cl- secretory channels?
YES, it does, so it is NET reabsorptive
Inflammation, histamine, toxins, and secretagogues promote the opening of _____ channels. As a result, the large intestine can become net secretory in the diseased state.
What is a clinical sign of a diseased state net secretory large intestine?
Large bowel secretory diarrhea