Final Exam GI Physiology: Large Intestine Flashcards Preview

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Flashcards in Final Exam GI Physiology: Large Intestine Deck (9)
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1

What are the 4 luminal secretions of the large intestine?

Mucin
HCO3- (exchanged for Cl-)
H+ (exchanged for Na+)
K+ (in response to aldosterone)

2

What 2 paracrine substances does the large intestine secrete?

Histamine and prostaglandin (vasodilators)

3

What is the 1 endocrine substance secreted by the large intestine?

GLP-1

4

Na+ and Cl- are largely reabsorbed in the ___________ after having escaped reabsorption in the small intestine.

large intestine

5

What 2 nerves are responsible for large intestine cholinergic and VIPergic stimulation?

Vagus n. and Pelvic n.

6

Does the large intestine have luminal membrane Cl- secretory channels?

YES, it does, so it is NET reabsorptive

7

Inflammation, histamine, toxins, and secretagogues promote the opening of _____ channels. As a result, the large intestine can become net secretory in the diseased state.

Cl- channels

8

What is a clinical sign of a diseased state net secretory large intestine?

Large bowel secretory diarrhea

9

The equine large intestine is the site of microbial fermentation and _____ production.

VFA production