Exam 2: Borrelia, Brachyspira, and Treponema Flashcards Preview

Bacteriology > Exam 2: Borrelia, Brachyspira, and Treponema > Flashcards

Flashcards in Exam 2: Borrelia, Brachyspira, and Treponema Deck (35)
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1
Q

gram (-), loosely coiled spirochete which commonly cause arthropod borne infections

A

Borrelia

2
Q

T/F Boorrelia are rapid growing

A

F. slow

3
Q

T/F. Borrelia are microaerophilic

A

T

4
Q

T/F Borrelia have circular chromosomes

A

F Linear

5
Q

Which spp. of Borrelia cause lyme dz?

A

B. burgdorferi

6
Q

Which spp. of borrelia causes avian septicemic borreliosis

A

B. anserina

7
Q

Which spp. of Borrelia causes relapsing fever borrelia and how is it spread?

A

B. recurrentis, spread by human body louse

8
Q

which type of tick transmits lyme dz

A

ixodes scapularis

9
Q

Which spp can get lyme dz

A

humans, dogs, horses, cattle, shep

10
Q

after a tick ingests Lyme infected blood from an animal, spirochetes up regulate expression of _______, which is essential for virulence in mamals

A

Outer surface protein

11
Q

What is the main virulence factor of Borrelia

A

LPS

12
Q

What is the importance of LPS in borrelia spp.

A

Ability to hide out in L forms, spherplast, cyctic dormant form in the host

13
Q

where does borrilia burgdorferi LPS transform from Osp C to Osp A

A

In the midgut of tics

14
Q

WHere does B. brgdorferi LPS transform from Osp A to Osp C?

A

in the salivary gland of ticks

15
Q

What Osp is transferred from ticks to mammals?

A

Osp C

16
Q

T/F in the case of canine Lyme disease an antibody titer does not predict illness

A

T

17
Q

List some methods of Dx of Lyme Dz

A
  1. direct detection in host tissue
  2. Culture and isolation
  3. Serology (SNAP), western blot, ELISA
18
Q

Tx for lyme dz

A

doxycycline or minocycline

19
Q

What are the two types of lyme vaccine?

A
  1. OSPA

2. OSPC which kills tick when feeds

20
Q

Which spp. of Brachyspira causes swine dysentery in growing pigs?

A

B. hyodysenteriae

21
Q

WHich spp of Brachyspira causees Intestinal spirochetosis in animals and humans?

A

B. pilosicoli

22
Q

Which spps. of brachyspira have a controversial role in disease?

A

B. intermedia
B. mudochii
B. innocens
B. canis

23
Q

Anaerobic spirochete agent of swine dysentery

A

B. hyodysenteriae

24
Q

Where is B. hyodysenteriae an obligate pathogen?

A

swine colon (and mice)

25
Q

T/F B. hyodysenteriae survives well in the environment

A

F. poorly survives, but will survive in anaerobic environ.

26
Q

Where in the environment can Bracyspira hyodsenteriae survive?

A

anaerobic places

manure

27
Q

What are the virulence factors of Brachyspira hyodesenteriae

A
  1. cytotoxin
  2. Hemolysis
  3. LPS
28
Q

What is the route of transmission of Brachyspira hyodesenteriae

A

Fecal - oral

29
Q

Where are lesions from Brachyspira hyodesenteriae found?

A

Lg intestine only

30
Q

How can you Dx Brachyspira hyodesenteriae

A

Direct staining
Anaerobic culture
PCR
Histopathology and silver staining

31
Q

Which spirochete causes syphilis?

A

Treponema pallidum

32
Q

T/F. Treponema can not be cultivated in the lab

A

T

33
Q

What is PDD

A

Papillomatous Digital dermatitis “Hairy heel warts” Treponema infection in cattle, causes lameness

34
Q

What is the Tx for PDD?

A

Spraying feet with abx, foraldehyde foot baths,

35
Q

What is Treponema paraluis- cuniculi?

A

Rabbit syphilis/ vent dz