Flashcards in Enzyme III Deck (8)
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1
Q
Heterotropic allosteric modifiers
A
- Structurally different from the substrate
- May be an activator or an inhibitor
2
Q
What is the role of cAMP in the regulatory pathways of phosphofructokinase and fructose 1,6-bisphosphatase?
A
Increase cAMP
Activate gluconeogenesis &
Inhibit glycolysis
3
Q
Allosteric inhibitor_____ the [S] required for 50% activity.
A
Increases
4
Q
Homotropic allosteric modifiers
A
- Usually a substrate
- Will only activate the enzyme
5
Q
Draw cooperativity plot
A
6
Q
Binding at the allosteric site cause a _______change.
A
Conformational
7
Q
Allosteric site
A
A binding site on the enzyme that is different from the active site
8
Q
Allosteric activator _____the [S] required for 50% activity.
A
Decrease