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Flashcards in Endocrinology Deck (659)
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121

In axonal transport, what determines the direction of transport of proteins?

Polarity

122

Parvocellular areas synthesise releasing and inhibitory substances which influence...

Tropic-hormone production of the adenohypophysis

123

Hypophyseotrop hormones

Hypothalamic substances that influence production + release of the pituitary gland

124

Give the parvocellular hormone systematic names

  • RH/RF (Releasing hormone/ Releasing factor)
  • IH/IF (Inhibiting hormone/ Inhibiting factor)
  • '+' (Facilitates synthesis + secretion hormones)
  • '-' (Inhibits hormone synthesis and release)

E.g TSH-RH = Thyrotropin hormone releasing hormone

125

In adenohypophyseal systematic naming, what do the following abbreviations mean (Prior to 'RH' or 'RF')?

  • T
  • C
  • Gn
  • G
  • P
  • M

  • T = Thyrotropin, TSH
  • C = Corticotropin, ACTH
  • Gn = Gonadotropin, FSH/LH
  • G = Growth hormone, STH
  • P = Prolactin, PRL
  • M = Melanocyte stimulating hormone, MSH

126

  1. TSH+
  2. Thyroliberin

127

  1. ACTH+
  2. Corticoliberin

128

  1. FSH+, LH+
  2. Gonadoliberin

129

  1. GH+
  2. Somatoliberin

130

  1. PRL+
  2. VIP, TRH

131

  1. MSH+
  2. MSH-RH

132

List the releasing factors (short name)

  • TRH
  • CRF
  • GnRH
  • GRF
  • PRF
  • MRF

133

Function: Thyrotropin-releasing hormone

  • Stimulates thyroid gland
  • Stimulates hormone release

134

Function: Corticotropin-Releasing Factor

  • Adrenocorticotropin (ACTH) stimulating hormone
  • Facilitates synthesis + release of:
    • ACTH
    • MSH
    • Endogenous opiates
  • Stimulating + splitting + synthesis of POMC

135

Function: Gonadotropin-releasing hormone

  • Facilitates synthesis + release of:
    • FSH (Follicle stimulating hormone)
    • LH (Luteinising hormone)
  • In males + females

136

Function: Growth hormone releasing factor (GRF)

Synthesis + release of growth hormone

137

Function: Prolactin-releasing hormone (PFR)

  • Prolactin synthesis + release
  • Lactation
  • Ovulation in the rat

138

What are the main parvocellular inhibiting factors?

  • Dopamine
  • Somatostatin
  • GABA
  • VIP

139

In adenohypophyseal systematic naming, what do the following abbreviations mean (Prior to 'IH' or 'IF')?

  • G
  • P
  • M

  • G = Growth hormone, somatotropin, STH
  • P = Prolactin, PRL
  • M = Melanocyte-stimulating hormone, MSH

140

  1. TRH-, PRL-
  2. TSH-IH, PRL-IH

141

  1. GH-
  2. GH-IH, somatostatin

142

  1. PRL-
  2. PRL-IH

143

  1. GH+
  2. MSH-IH, Melatostatin

144

  1. General, an indirect inhibitor
  2. Norepinephrine

145

  1. General, an indirect inhibitor

146

Function: GIF

  • Systematic name for Somatostatin
  • GIF = Growth hormone inhibiting factor
  • Somatotropin inhibiting hormone

147

Function: PIF

  • Systematic name for inhibiting factor of prolactin release + production
  • Regulated by dopamine
  • Hypothalamic peptide is known to decrease prolactin production

148

  1. PRL+, GIF
  2. GIF+ In the pancreas

149

  1. PRL+
  2. Substance-P antagonist

150

  1. GH, PRL+
  2. MSH-IH, melanostatin