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Flashcards in Endocrine Deck (20)
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1
Q

infant with marcroglosssia, unbilical hernia, coarse facial features

A

cretinism (congenital hypothyroidism)

2
Q

painful tender thyroid. hypothroidism. common post viral

A

de Quervains thyroiditis

associated iwth HLA B27, give aspirin

3
Q

fibrous hyroid, woody nodule

A

reidel throiditis (surgery)

4
Q

step to work up a thyroid nodule?

A

1 = TSH level
Low TSH → RAIU scan
high TSH –> Observe with serial U/S
Non-Functioning: → FNA

Normal/elevated TSH → U/S → Bx if: solid and >1 cm, cystic nodule >2com, nodules >.5 cm in pts with RF

5
Q

what is required for intestinal Ca2+ absorption?

A

vitamin D

6
Q

what hormones maintain a normal Ca2+

A

parathyroid hormone
calcitriol (vit D)
(bothin incrrease when Ca2+is low)

7
Q

what is the MC cause of 2ndry hyperparathyroidism?

A

CKF (low vitamin D –> low Ca2+ –> high PTH)

8
Q

trousseau’s and Chvostek sign and inc tendon reflexes make you think of what?

A

hypocalcemia

9
Q

prolonged QT interval

A

hypocalcemia

10
Q

shortened QT interval

A

hypercalcemia

11
Q

tx for hypocalcemia

A

calcium gluconate

po cacium and vitamin D

12
Q

Tx for hypercalcemia

A

IV saline –> furosemide

calcitonin+ bisphonsphonates if severe

13
Q

genetic mutation of type i collagen. severe osteoporosis, sponatneous childhood fx and blue tinted sclera

A

osteogenesis imprefecta

14
Q

lab result for a pt with renal osteodystrophy

A
low Ca2+ (dec vit D production)
high phosphate (inability to secrete) 
high PTH (response to low Ca2+)
15
Q

punched out lesions on skull = ___
cotton wool spots on skull = ___
salt and pepper skull = ____

A

Multiple myeloma
pagets dz
renal osteodystrophy

16
Q

tx for renal osteodystrophy

A

phosphate binders (calcium carbonate)
vitamin D
cinacalcet (lowers PTH)

17
Q

mc cause of adrenocortical insufficiency?

A

chronic steroid use

18
Q

MC cause of hyperaldosteronism

A

renal artery stenosis

19
Q

medications for prolactinomas

A

carbergoline

bromocriptine

20
Q

med for acromegaly

A

octreotide