Flashcards in Endocrine Deck (254)
What two tumors can secrete ACTH?
small cell lung
What does lack of inhibition by dexamethasone mean?
ectopic ACTH production
What is another name for Primary Hyperaldosteronism?
Would Conn Syndrome have low or high plasma renin?
What drug would be used in Conn Syndrome?
What causes Secondary Hyperaldosteronism?
Renal perception of low intravascular volumes
Would Secondary Hyperaldosteronism present with high or low plasma renin?
What is the treatment for Secondary Hyperaldosteronism?
What is secondary adrenal insufficiency?
decreased response to ACTH
What cells does a neuroblastoma originate from?
Which does not cross the midline, Wilms or Neuroblastoma?
Wilms = not cross midline
Neuroblastoma = can cross
What is an easy mechanism to diagnose Neuroblastoma?
homovanillic acid in urine
What gene is neuroblastoma associated with?
What is the tumor marker for Bombesin?
What is homovanillic acid a breakdown product of?
What cells does a pheochromocytoma originate from?
Which three diseases can result in a pheochromocytoma?
What is found in the urine during a pheochromocytoma?
What is VMA a breakdown product of?
epinephrine and norepinephrine
Which is given first during a pheochromocytoma, α-blockers or β-blockers?
Why does hypothyroidism present with hypercholesterolemia?
thyroid hormone upregulates LDL receptor
Why does hyperthyroidism present with hypocholesterolemia?
increase LDL receptor expression
What are the two autoantibodies present during Hashimotos?
What is the HLA haplotype most often found during Hashimotos Thyroiditis?
Is Hashimotos a tender or nontender thyroid?
What structure is present during Hashimotos Thyroiditis?
What type of inflammation is present during de Quervain thyroiditis?
Is de Quervain painful or painless?
What is the course of thyroid hormone release during DeQuervains?
followed by hypo