Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHAR 557 > Eating Disorders > Flashcards

Eating Disorders Flashcards

1
Q

T or F: There’s no specific BMI/wt req’d to be dx’ed w/ anorexia nervosa.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

BMI assoc w/ mild anorexia nervosa (DSM-5)

A

≥ 17 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

BMI assoc w/ extreme anorexia nervosa

A

BMI < 15 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Behaviour assoc w/ bulimia nervosa.

A

Binge eating + purging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the main problem with pts who suffer from anorexia nervosa?

A

they have an intense fear of gaining wt/getting fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Extreme bulimia nervosa is defined as…

A

≥ 14 compensatory (purging) behaviours per week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Extreme bulimia nervosa is defined as…

A

≥ 14 compensatory (purging) behaviours per week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which eating disorder doesn’t have specific BMIs assoc w/ it?

A

bulimia nervosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Underwt BMI:

A

< 18.5 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Obese BMI:

A

> 30 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Obese BMI:

A

> 30 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What’s the deadliest psychiatric illness?

A

Anorexia nervosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do eating disorders usually begin?

A

Stressful events

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What’re the 2 subtypes of anorexia nervosa?

A
  1. restricting type (no regular binge eating/purging during the last 3 mths), and…
  2. binge eating/purging type (regular binge eating/purging during the last 3 mths)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Consequences of amenorrhea in anorexic women?

A
  1. reduced BMD (osteoporosis)
  2. decreased growth velocity
  3. no libido
  4. unexpected pregnancies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Consequences of amenorrhea?

A
  1. reduced BMD (osteoporosis)
  2. decreased growth velocity
  3. no libido
  4. unexpected pregnancies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

At a neurobiological level, how does anorexia nervosa cause amenorrhea?

A

Starvation/chronic stress > increased cortisol release > suppression of hypothalamic pituitary gonadal axis (and other axes too) > reduction in follicle development > reduction in estrogen release > reduction in uterine lining proliferation > reduction in periods > amenorrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

T or F: Return of menstrual cycle in anorexic women is related to the amt of body fat.

A

F (it’s related to the amt of serum estrogen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What body systems are negatively impacted by anorexia nervosa?

A

All of them since they depend on nutrients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

T or F: Most CV abnormalities return to baseline with wt restoration.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

T or F: Most CV abnormalities return to baseline with wt restoration.

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Why is domperidone used for delayed stomach emptying, but metoclopromide is not in

A

Metoclopramide crosses the BBB > extrapyramidal sx’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Is estrogen replacement tx effective for amenorrheic wom for increasing bone loss? And who?

A

No

24
Q

Is estrogen replacement tx effective for amenorrheic wom? Andy who

A

No

25
Q

Bisphosphonates: evidence for use in anorexic women for preventing bone loss?

A

There’s mixed evidence wrt preventing fractures in pts w/ eating disorder

26
Q

T or F: Bisphosphonates are able to prevent bone fractures in adult women W/O anorexia.

A

T

27
Q

Best way to prevent bone breakdown in the body?

A

Weight recovery

28
Q

Which one is preferred: NG tube feeding or IV feeding? Why?

A

NG tube feeding > it’s cheaper and safer

29
Q

Refeeding syndrome - sx’s?

A

gastric bloating, nausea, edema, diarrhea

30
Q

When does refeeding syndrome occur?

A

when the malnourished pt is fed a high carb load

31
Q

What exactly happens during a refeeding syndrome episode?

A

pt given carb-heavy load > body produces lg amt of insulin > rapid uptake of phosphates, Mg, K into cells > decrease in serum electrolytes + fluid retention > cardiac changes (due to hypoK) > HF > death (possibly)

32
Q

When are cardiac issues the most likely during nutrition reintroduction to malnourished pts?

A

In the beginning

33
Q

Most problematic electrolyte shift in refeeding syndrome?

A

K > hypoK will cause cardiac issues

34
Q

How to avoid refeeding syndrome?

A

Initiate refeeding SLOWLY

35
Q

Non-pharm tx for anorexia nervosa?

A

Psychotx (CBT)

36
Q

When does pharm tx become effective for anorexia nervosa pts?

A

when pt gains wt

37
Q

Pharm options for anorexia nervosa:

A
  1. Zinc
  2. antipsychotics
  3. antidepressants
38
Q

Why is Zn given to anorexia nervosa pts?

A

For wt gain, and to benefit mood/anxiety

39
Q

Efficacy of Zn in anorexia nervosa?

A

Mixed evidence

40
Q

Which antipsychotics are recommended in anorexia nervosa pts?

A

Olanzapine (2nd gen) ONLY

41
Q

T or F: Bc olanzapine is an antipsychotic, it helps with the cognitions/obsessionality of anorexia nervosa

A

F

It only helps w/ gaining wt (modest)

42
Q

Olanzapine AEs (it’s used for anorexia nervosa)

A

EPS (akathisia, acute dystonia, parkinsonism, tardive dyskinesia), antichol activity, QT prolongation

43
Q

What kind of antidepressants are recommended in anorexia nervosa pts?

A

SSRIs

44
Q

How do antideps help w/ anorexia nervosa?

A

They may help w/ comorbid depression and OCD AFTER wt restoration

45
Q

T or F: SSRIs help with wt gain in anorexic pts.

A

F

46
Q

T or F: TCAs are recommended in anorexic pts.

A

F

47
Q

What should the focus be in anorexia nervosa tx?

A

The behavioural aspect (CBT)

48
Q

T or F: Bulimic pts are often underwt

A

F

They’re often either on upper end of normal wt or overwt

49
Q

Non-pharm tx for bulimia nervosa

A

CBT (most effective psychotx)

50
Q

T or F: CBT is more effective than pharm tx for bulimia nervosa

A

T

51
Q

Drugs of choice for bulimia nervosa

A

SSRIs

52
Q

How do SSRIs help w/ bulimia nervosa?

A

They reduce binge-purge episodes (regardless of comorbid depression)

53
Q

Most studied SSRIs for bulimia nervosa

A

fluoxetine, citalopram, sertraline

54
Q

What other medication has been used for tx’ing bulimia nervosa?

A

Topiramate

55
Q

What specific AE of topiramate prevents it from being normally used?

A

Brain fog

56
Q

Besides the binge-eating and purging, what else should we be tx’ing in bulimic pts?

A
  1. electrolyte abnormalities
  2. constipation
  3. malnutrition

PHAR 557 (36 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions