Dyspnea Flashcards

1
Q

What interventions would reduce the exacerbations of COPD?

A
  • Smoking cessation
  • Long acting bronchodilator
  • Inhaled corticosteroid
  • Influenza vaccine
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2
Q

What are the two most common causes of dyspnea and wheezing in adults?

A
  • COPD

- Asthma

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3
Q

Describe the typical presentation of asthma.

A
  • Asthma => begins earlier in life, may/not associated with cigarette smoking, episodic exacerbations with return to normal baseline lung functioning
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4
Q

Describe the typical presentation of COPD.

A
  • COPD => present in midlife or later, usually result of long term smoking, progressive disorder, pulmonary function never return to normal
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5
Q

What are the mainstays of acute asthma and COPD exacerbations?

A
  • Oxygen
  • Bronchodilators (beta 2 agonist for rapid bronchodilation)
  • Steroids
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6
Q

What clinical signs of dyspnea should be noted in patients who complain of SOB?

A
  • Hypoxemia => cyanosis of the perioral region or digits

- Pulse oxygen should be taken

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7
Q

What are the various classes of bronchodilators?

A
  • Beta 2 agonists => rapid bronchodilation and reduce airway obstruction
  • Anticholinergic agents (ipratropium) => may work synergistically with the beta 2 agonist
  • Corticosteroids act to reduce the airway inflammation that underlies the acute exacerbation
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8
Q

Define chronic bronchitis.

A
  • Cough and sputum production on most days for at least 3 months during at least 2 consecutive years
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9
Q

Define emphysema.

A
  • SOB caused by the enlargement of respiratory bronchioles and alveoli caused by destruction of lung tissue
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10
Q

What are other etiologies of COPD apart from smoking?

A
  • Second hand smoke
  • Occupational exposures to dusts or chemicals
  • Alpha1 antitrypsin (rare, but more common in whites) => when emphysema develops
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11
Q

What pathologic changes are associated with COPD?

A
  • mucous gland hypertrophy with hypersecretion
  • ciliary dysfunction
  • destruction of lung parenchyma
  • airway remodeling
  • All resulting in narrowing of the airways/airway obstruction, poor mucous clearance, cough, wheezing, and dyspnea
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12
Q

What are symptoms of COPD?

A
  • Daily cough that can be productive of white, thick mucus
  • Cough may worsen and produce yellow/green mucus
  • Wheezing
  • Exacerbations often with viral/bacterial infections
  • Dyspnea (represents a decrease in lung function by 1/2)
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13
Q

What are signs of advanced COPD?

A
  • Barrel chest => increased anteroposterior chest diameter
  • Distant heart sounds=> hyperinflation of the lungs
  • Distant breath sounds
  • Prolonged expiratory wheezes
  • Use accessory muscles to breath, tachypneic
  • Hypoxic
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14
Q

What are the xray findings in COPD?

A
  • Unless the COPD is severe there will be NO xray findings (normal)
  • In severe cases: hyperinflation of the lungs, increased posteroanterior diameter, flattening of diaphragms, and bullae
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15
Q

What normal, age related changes are seen in spirometry?

A

With normal aging FVC and FEV-1 both decrease => the FVC/FEV-1 ratio is >0.7

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16
Q

Describe the type of COPD and treatment:

  • FVC/FEV-1 ration 80% predicted
  • With or w/o symptoms
A

Mild COPD => short acting bronchodilator

  • beta 2 agonists => albuterol
  • anticholinergics => ipratropium
17
Q

Describe the type of COPD and treatment:

- FVC/FEV-1 ration

A
  • Moderate COPD => long acting bronchodilator
    • beta 2 agonists => salmeterol
    • anticholinergics => tiotropium
    • Oral methylxanthines => phylline and theophylline (higher toxicity)
18
Q

Describe the type of COPD and treatment:

- FVC/FEV-1 ration

A
  • Severe COPD => inhaled steroids

- Fluticasone, triamcinolone, mometasone

19
Q

Describe the type of COPD and treatment:

- FVC/FEV-1 ration

A
  • Very severe COPD => Consider oxygen therapy

- oxygen is the only therapy known to decrease mortality and must be worn 15hrs/day

20
Q

What is the benefit of smoking cessation to a patient with COPD?

A
  • Smoking cessation reduces the rate of further deterioration to that of a nonsmoker
21
Q

What vaccines should all COPD patients receive?

A
  • Pneumococcal and annual flu vaccinations
22
Q

What are common precipitants of acute COPD exacerbations?

A
  • Viral or bacteria infections

- Be careful to exclude => pulmonary embolism, CHF, and MI

23
Q

What are the most common bacteria implicated in purulent COPD exacerbations?

A
  • Pneumococcus
  • Haemophilus influenzae
  • Moraxella catarrhalis
  • Klebsiella
  • Pseudomonas