Droperidol Flashcards
0
Q
CNS effects
A
Liters normal CNS transmission
1
Q
Mechanism of action
A
Acts centrally at sites where dopamine, NE, and SE act
2
Q
Anti-emetic
A
Effect at red astrocytes in the chemo-receptor trigger zone
3
Q
A-adrenergic
A
Blocking ability
4
Q
GABA receptors
A
May occupy on post synaptic membrane causing build up of DA on the inter synaptic cleft
5
Q
Anesthesia a
A
Neuroleptic anesthesia
6
Q
Cardiovascular effects
A
Decrease SVR, MAP,
Nothing on CO or Contractility
7
Q
EKG change
A
Prolonged QT interval
Delayed repolarization
Torsades de pointes
8
Q
CNS effects
A
No human data on CBF
worsen extra pyramidal symptoms
9
Q
Contraindicated in
A
Parkinson’s
10
Q
Uses
A
Antiemetic 0.625-1.25 mg IM/IV in adults
11
Q
Onset
A
5-8 mins
12
Q
VD
A
2 L/kg
13
Q
Duration of faction
A
3-6 hours
14
Q
Elimination half life
A
1.7-2.2 hours
