DLA 15 Flashcards

1
Q

general structure of an amino acid?

A

carboxylic group

R group

H

amino group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

All AA’s are chiral except

A

glycine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Naturally occurring amino acids are in what what configuration?

A

L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Why is proline different?

A

It has a ring structure

lead to kinks in protein chains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where is proline found a lot in?

A

collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What AA’s are nonpolar and aliphatic ?

A

glycine, alanine and proline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What AA’s are nonpolar, aliphatic, and have branched side chains?

A

Valine, leucine, and isoleucine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What AA’s have aromatic side chains?

A

phenylalanine, tyrosine and tryptophan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What amino acids contain sulfur?

A

methionine and cysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What AA can make disulfide bonds?

A

cysteine by oxidation and reduction breaks the bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What amino acids are polar and non-charged?

A

asparagine and glutamine

Serine and Threonine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What AA’s can be phosphorylated and glycosylated?

A

Serine & threonine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What AA’s have negative (acidic) side chains at physiological pH?

A

Aspartate and glutamate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What AA’s have positive (basic) side chains?

A

Arginine and lysine

SOMETIMES histidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What AA is favorable in buffering the normal pH of cells?

A

Histidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is GABA formed?

A

decarboxylation of the a-carboxyl group of glutamate

17
Q

How is histamine formed?

A

decarboxylation of histidine

18
Q

How is serotonin made?

A

It is a derivative of tryptophan

19
Q

dopamine, norepinephrine and epinephrine are formed from what AA?

A

tyrosine

20
Q

How is dopamine made?

A

tyrosine is hydroxylated to dihydroxy-phenylalanine (L-DOPA)

L-DOPA is decarboxylated to dopamine, the first catecholamine.

21
Q

How are AA linked together?

A

peptide bonds

a carboxyl group of one amino acid and the a amino group of the following amino acid