Diseases of infancy and childhood Flashcards Preview

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Flashcards in Diseases of infancy and childhood Deck (25)
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1
Q

[term]

intrinsic abnormal process, primary error of morphogenesis

A

malformation

2
Q

[term]

amniotic band compressing parts of fetus

A

disruption

3
Q

[term]

due to abnormal biomechanical process like that of club feet

A

deformations

4
Q

[term]

one initiating aberration leading to cascade of anomalis

A

sequence

5
Q

[term]

constellation of congenital anomalies that are pathologically related, cannot be explained by single, localized, initiating defects

A

malformation syndrome

6
Q

[name the possible cause]

mental retardation, cataracts, sensorineural healing loss, cardiac anomalies

A

rubella

7
Q

[name the possible cause]

short deformed limbs

A

thalidomide

phocomelia

8
Q

[name tha possible cause]

microcephaly, growth retardation, facial anomalies, reduced mental capacity

A

alcohol

9
Q

week of AOG that is extremely susceptible to teratogenesis

A

3rd to 9th week

10
Q

pulmonary surfactant is composed of what compound?

A

dipalmitoylphsphatidylcholine (DPPC)

11
Q

retinopathy of prematurity is due to ___ injury

A

hyperoxic

12
Q

when to give glucocorticoids for lung maturity

A

24 to 34 weeks AOG

13
Q

[disease entity]

premature, hematochezia, abdominal distension, circulatory collapse, pneumatosis intestinalis

A

necrotizing enterocolitis

14
Q

mediator implicated in necrotizing enterocolitis because it increases mucosal permeability

A

platelet activating factor

15
Q

most common cause of aplastic crisis in hemolytic anemia

A

parvovirus B19

16
Q

[what disease entity]

congenital bilateral absence of vas deferens, dilated pancreatic and salivary duct, meconium ileus

A

cystic fibrosis

17
Q

safest sleeping position in infatnts

A

supine

18
Q

second most common malignancy in children

A

neuroblastoma

19
Q

most common extracranial solid tumor of childhood

A

neuroblastoma

20
Q

[what disease entity]

homer-wright pseudorosettes, small round blue cells with mitosis, karyorrhexis and atypia, neuropil

A

neuroblastoma

21
Q

blueberry muffin baby, cross the midline

A

neuroblastoma

22
Q

[name this syndrome]

organomegaly, macroglossia, hemihypertrophy, omphalocele, andrenal cytomegaly

A

beckwidth-weidemann

WT2 gene

23
Q

[name this syndrome]

gonadal dysgenesis, early onset nephropathy (diffuse mesangial sclerosis), increased risk for wilms tumor

A

Denys-Drash Syndrome

WT1 gene

24
Q

cross the midline, homer-wright pseudorosettes, neuropil, blue berry muffin

A

neurobalstoma

25
Q

small round, blue cells, glands, glomerular sturcutres, fibroblastic stroma

A

wilms tumor