Devlopment L8 - oral developmental biology Odontogenesis 2 Flashcards Preview

Dentistry Module 4 > Devlopment L8 - oral developmental biology Odontogenesis 2 > Flashcards

Flashcards in Devlopment L8 - oral developmental biology Odontogenesis 2 Deck (23)
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1
Q

what is the name of the epitheliums that line the periphery of the enamel organ

A

inner and outer enamel epithelium

2
Q

during the bell stage the inner enamel epithelium cells differentiate and become tall columnar what?

A

pre-ameloblasts

3
Q

some cells between the inner enamel epithelium and stellate reticulum become spindle shaped forming which cell?

A

stratum intermedium

4
Q

the cervical loop is continuation of the inner and outer enamel epithelium.

the cervical loop is an part of the tooth germ in that, it gives rise to the?

A

dental papilla and dental follicle

5
Q

growth factors released from the cervical loop during the early stages of bell stage differnetiate the mesenchyme cells in to which cells?

A

dental papilla

6
Q

growth factors released from the cervical loop allow the Dental Papilla and the Inner enamel epithelium to mature, causing them to elongate and polarise.

this allows the Dental Papilla to invade the acellular zone.

what does the dental papilla mature in to

A

mature in to odontoblasts to form predentine then dentine

7
Q

IEE cells mature in to what?

A

Ameloblasts to form enamel

8
Q

once dentine has been laid down near the cusp, what does this activate?

A

the laying of dentine signals ameloblast to lay down enamel.

9
Q

the most cervical (cervical loop) portion of the enamel organ is responsible for the development of what?

A

root development

10
Q

bell stage is marked by two events called morphodifferentiation and histodifferentiation which happen simultaneously.

what is morphdifferentiation and histodifferentiation?

A

morphodifferentiation refers to the establishment of the shape of the crown

histodifferentiation refers to the “coming of age” moment when dental papilla cells differentiate to odontoblast and inner enamel epithelial cells become ameloblasts

11
Q

once the crown has been formed, the cercical loop starts to proliferate to give rise to what

A

hertwig’s epithelial root sheath.

the rooth sheath bends at 45 degrees towards the pulp narrowing the cervical opening.

12
Q

as the root sheath proliferates, the inner layer of the root sheath induces differentiation.

the differentiation causes adjacent dental papilla cells to odontblasts which then produce the dentine.

what affect does dentine have on the root sheath

A

as dentine is formed, it begins to minerlaise and disintergrate the adjacent rooth sheath?

13
Q

with the disintegration of the root sheath, gives access to dental folllicle cells to invade and interact with the dentine.

this interaction allows the follicle cells to differentiate to which cells

A

dental follicle cells differentiate to cementoblasts and lay down cementum

14
Q

the image shows a devloping tooth at late bell stage:

a layer of pre-dentine is forming and this will stimulate what?

A

the ameloblasts to synthesise and secrete enamel proteins

15
Q

odontoblast differentiate to become columnar in shape why is this?

A

odontoblast are protein secreting cells and the shape accomodates the abundance of rough ER and Golgi

16
Q

the initial enamel secreting cells formed are responsible for the formation of what?

A

for the formation the enamel-dentine junction

17
Q

once ameloblast have matured, what happens to the cell size

A

once matured cells regress in height to protect enamel surface

18
Q

image e

the red coloured stain shows what

the purple coloured stain identified as E shows what

A

red coloured stain shows dentine

purple coloured stain shows enamel

19
Q

pre-dentine is an organic matrix that makes up dentine before it is calcified. what collagens make up pre-dentine

A

collagen I, III, V, VI

20
Q

enamel is made up of two groups of protein what are their names

A

amelogenins - make up 90-95%

enamelins - make up 5-10%

21
Q

tooth chape determination is determined by the maturation and division of what

A

IEE cell division and IEE cell maturation

22
Q

what role does reduced enamel epithelium play

A

protection of enamel surface from resoprtion

provide and epithelial lined pathway for eruption

forms initial junctional epithelium

23
Q
A

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