Designing the Perfect Anti-Infective Agent and Introduction to Antibiotics PART 2 Flashcards Preview

MDCN 350: Course 1 > Designing the Perfect Anti-Infective Agent and Introduction to Antibiotics PART 2 > Flashcards

Flashcards in Designing the Perfect Anti-Infective Agent and Introduction to Antibiotics PART 2 Deck (9)
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1
Q

3 classes of antibiotics that are inhibitors of cell wall synthesis

A
  1. beta lactams (carbapenem, penicillin, monobactam, cephalosporin
  2. glycopeptides
  3. phosphonic acid.
2
Q

monobactams cover mainly gram ____

A

gram negatives. (ex/ aztreonam)

3
Q

T/F carbapenems are broad spectrum

A

true. examples include meropenem and ertopenem.

4
Q

examples of glycopeptides. good from gram positive or negative?

A

vancomycin, good for treating gram positive (like staph auereus, C. dif (gram positive bacilli), bacillus anthracis)

5
Q

5 classes of protein synthesis inhibitors

A
  1. aminoglycosides (tobramycin and genatmycin)–G-
  2. tetracyclines (doxycycline)– BS
  3. macrolides (clarithromycin and azithromycin), more gram positive.
  4. lincosamides (clindamycin, gram positive and some anaerobic gram negative)
  5. oxazolidinone
6
Q

broad spectrum antibiotic classes that inhibit protein synthesis

A
  1. tetracyclines (doxycycline)
  2. macrolides (clarithromycin, azithromycin)
7
Q

gram + pathogen antibiotic classes that inhibit protein synthesis

A
  1. lincosamides (clindamycin)
  2. oxazolidinones
8
Q

gram negative pathogen antibiotic classes that inhibit protein synthesis

A

aminoglycosides (gentamycin, tobramycin)

9
Q

4 classes of antibiotics that are inhibitors of NA synthesis and DNA syntheiss

A
  1. fluroquinolones (ciprofloxacin broad spectrum)
  2. rifamycins *rifampin)
  3. sulfonamides (broad spectrum like septra)
  4. nitroimizadoles (macrobid for UTI gram negative)