Oligosacharides attach to this AA and O-linked to make glycoprotein
Serine
Mnemonic = OG SER
Oligosachides attached to serine to form glycoprotein is synthesized in the ___
golgi bodies
Oligosaccharides attached to this AA is N-linked (to make glycoprotein)
Asparagine
Oligosaccharide attached to asparagine to make glycoprotein is synthesized in the
Endoplasmic reticulum
Cell surface antigenicity is due to what complex molecule?
Glycoprotein
[Complex molecule]
Transport proteins with glycoprotein
Transferrin
Ceruloplasmin
[Complex molecule]
Hormone that contains glycoprotein
HCG, TSH
[Complex molecule]
lubricant protective int he GIT and urogenital tract that has glycoprotein
mucin
[Complex molecule]
Glycosaminoglycans is mostly made of
CHO
Glycosaminoglycas are unbranced polysaccharides consisting of alternating ___-
acidic sugar-aminosugar
[Glycosaminoglycans]
What are examples of acid sugars
Glucuronic Acid
Iduronic acid
[Glycosaminoglycans]
examples of amino sugar
Glucosamine
Galactosamine
Which GAG is not linked to a proteoglycan core
hyaluronic acid
[Glycosaminoglycans]
Needed for cell migration and wound repair
hyaluronic acid
[Glycosaminoglycans]
seen in carilage
Chondroitin sulfate
most abundant
[Glycosaminoglycans]
maintains corneal transparency
keratan sulfate
[Glycosaminoglycans]
anticoagulat
heparin
[Glycosaminoglycans]
receptor for cell growth and cell-cell communication
heparan sulfate
[Glycosaminoglycans]
maintain GAG of skin
dermatan sulfate
[Glycerophospholipids]
What bond maintains the binding of an R-OH to the diacylglycerol
Phosphodiester bind
[Glycerophospholipids]
Most abundant glycerophospholipid
lecithin
[Glycerophospholipids]
storage of choline component of acetylcholine
Phosphatidylcholine
[Glycerophospholipids]
cephalin, cell membrane inner leaflet
phosphatidylethanolamine
[Glycerophospholipids]
plays a role in apoptosis
Phosphatidylserine
[Glycerophospholipids]
reservoir of arachidonic acid in cell membrane
phosphatidylinositol
[Glycerophospholipids]
source of inositol triphosphate + DAG
phosphatidylinositol
[Glycerophospholipids]
lung surfactant
Dipalmitoyllecithin
[Glycerophospholipids]
cross reacts with antibodies to syphilis
Cardiolipin
What is the backbone of sphingophospholipids?
Sphingosine
What is the only significant sphingophospholipid in humans?
Sphingomyelin
___ is a complex molecule that is a derivative of ceramide in which a long chain FA is attached to sphingosine backbone
Glycosphingolipids
[Glycosphingolipids]
if hyrdogen atom is ttached
Ceramide
[Glycosphingolipids]
if glucose or galactose is attached
Cerebroside
[Glycosphingolipids]
if a di-, tri-, or tetrasaccharide is attached
globoside
[Glycosphingolipids]
if N-acetylneuraminic acid is attached
ganglioside
[Glycosphingolipids]
if sulfated glucose is attached
sulfatide
What contributes to the asymmetry of the cell membrane outer leaflet?
glycosphingolipids
___ are derived from 20 carbon FA arachidonic acid, cleaved by phospholipase A2
Eicosanoid
What enzyme produces prostaglandin and thromboxane?
Cyclooxygenase
What enzyme produces leukotrienes?
lipooxygenase
[Eicosanoids]
protect gastric mucosa
prostaglandin
[Eicosanoids]
Promotes platelet adhesion and aggregation
Thromboxane
[Eicosanoids]
stimulate vasodilation, inhibits thrombosis
Prostacyclin
[Eicosanoids]
Keeps PDA patent, used for erectile dysfunction
Alprostadil (PGE1)
[Eicosanoids]
Results in vasodilation and relaxation of smooth muscle used to induce labor
Prostaglandin E2
[Eicosanoids]
results in vasoconstriction and contraction of muscle, stimulates uterine contraction
PGF2alpha
[Eicosanoids]
slow reacting substances,
potent airway constrictors
LTC4
LTD4
LTE4