Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Bacteriology > Clamydia > Flashcards

Clamydia Flashcards

1
Q

What kind of stain would you use for chlamydia?

A

Geimsa stain or immunofluorescence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The cell wall of chlamydia resembles what?

A

it resembles the cw of Gram (-) bacteria with relatively high lipid content

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

are Beta-lactam antibiotics suitable for treatment of chlamydia?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the two morphological forms of Chlamydia?

A
  • Elementary body is infectious

- Reticulate body is metabolically active

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

characteristics of elementary body?

A
  • resistant to harsh environments
  • infects mononuclear phagocytes
  • prevents fusion of phagosome with lysosome
  • enter the cell via endocytosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Characteristics of reticulate body?

A
  • replicated inside vesicles by fission
  • Inclusion bodies
    only intracellular
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What drugs can you use Giemsa stain on?

A

Chlamydia, Borrelia, Rickettsiae, Trypanosomes, Plasmodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

chlamydia can not make its own what?

A

they can not make their own ATP. They are obligate intracellular organisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why is the chlamydial cell wall unusual?

A

because it lacks muramic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the chlamydia trachomatis serotypes?

A
  • Types A,B,C
  • Types D-K
  • Types L1, L2, L3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Types A, B and C cause what?

A

ABC = Africa/Blindess/Chronic

  • Chronic infection
  • causes blindness due to follicular conjunctivitis in Africa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Types D-K cause what?

A
  • STDs
  • ectopic pregnancy
  • neonatal pneumonia (staccato cough)
  • neonatal conjunctivitis
  • PID
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Chlamydia trachomatis types L1, L2, L3 cause what?

A

Lymphogranuloma venereum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

receptors for elementary bodies are primarily restricted to what?

A

non ciliated columnar, cuboidal and transitional epithelial cells found on mucous membrane of urethra, fallopian tubes, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

whats the most commonly reported infectious disease in america?

A

Chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Chlamydia causes this specific disease which is the leading cause of preventable blindness in children.

A

Trachoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Untreated chlamydial infections can lead to severe reproductive complications like?

A
  • Pelvic inflammatory disease
  • Infertility
  • Ectopic pregnancy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What species are included in Chlamydia?

A
  • Trachomatis
  • Pneumoniae
  • Psittaci
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Chlamydia pneumoniae and psittaci cause what?

A

Atypical pneumonia

20
Q

Chlamydia is transmitted mainly during?

A

Vaginal or anal sex. also possible through oral sex

21
Q

Chlamydia initially infects what kind of cells?

A

single cell columnar epi layers. (endocervix, urethra in men)

22
Q

what are some physical manifestations of chlamydia?

A
  • Mucopurulent cervicitis

- cervical ectropian

23
Q

If left untreated, infection can spread ascend to where?

A

it can ascent the endometrial epithelium to the fallopian tubes

24
Q

What are the steps on how Trachoma eventually leads to blindness?

A

Begins with follicular conjunctivitis –> Corneal ulceration and scarring with in turned eyelashes –> blindness

25
Q

What syndrome is a rare complication of PID which is 5 times more likely to be caused by chlamydia than by N. gonorrhoeae?

A

Fitz-Hugh-Curtis syndrome

26
Q

This specific syndrome is initiated by genital infection with C. Trachomatis?

A

Reiter’s syndrome (reactive arthritis)

27
Q

Reiter’s syndrome mostly occurs in…?

A

Young males and HLA-B27 (PAIR)

28
Q

What are the common diseases associated with Reiter’s syndrome?

A
  • Urethritis
  • Polyarthritis
  • Conjunctivitis
29
Q

What precipitate Reiter’s syndrome?

A
  • nongonococcal venereal disease and infectious diarrhea.
30
Q

How does Lymphogranuloma venereum enter (LGV)?

A

through skin breaks or crosses epithelial cells of mucous membranes

31
Q

The primary stage of LGV is marked by the formation of what?

A

Painless herpetiform ulceration at the site of inoculation

32
Q

LGV is highly prevalent where?

A

Africa, Asia, and South America and mostly in Homosexual Men

33
Q

What is the tertiary stage of LGV called which can occur years after initial infection?

A

Anogenitorectal syndrome

34
Q

What is inguinal syndrome?

A

characterized by painful inguinal lymphadenitis and associated constitutional symptoms.

35
Q

LGV organism travels via what to multiply where?

A

It travels via the lymphatics and multiplies within mononuclear phagocytes in regional LN

36
Q

What is the drug of choice for all chlamydia?

A

Tetracycline derivatives (doxycycline, azithromycin)

37
Q

What drug should you use specifically for the treatment of LVG?

A

Doxyclycline

38
Q

Antibiotics for chlamydia are only effective against what?

A

Reticulate bodies

39
Q

what causes pneumonia in newborns (birth - 6 weeks)

A

Group B streptococcus and E. Coli

40
Q

Chlamydia causes pneumonia in what ages?

A
  1. Children (6 weeks - 18 years)

2. Adults (40-65 years)

41
Q

C. pneumoniae causes 10-20% of what among adults?

A

Community-acquired pneumonia

42
Q

Clinical presentation of c. pneumoniae infection?

A

most infected persons are asymptomatic and have mild respiratory illness

43
Q

The criteria for the diagnosis of acute C. pneumoniae infection is what?

A

Single IgM titer or >1:16
or
A fourfold increase in IgG titer

44
Q

Treatment for C. Pneumoniae?

A

Erythormycin, Azithromycin, and Clarithromycin

45
Q

How is C. psittaci transmitted?

A

by inhalation of dust contaminated with respiratory secretions or feces of infected birds especially parrots.

46
Q

What kind of disease is C. psittaci?

A

A Zoonotic disease

47
Q

about 45% of all cases of gonorrhea have what co-existing with them?

A

Chlamydial infections

Bacteriology (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions