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Flashcards in circulatory system Deck (102)
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1

type of tissue blood is

specialised connective tissue

2

what does blood consist of

liquid matrix(plasma) and cellular portion of formed elements

3

percentage of plasma and formed elements

plasma 55%
formed elements 45%

4

describe the plasma

straw-coloured, viscous fluid,matrix of the blood

5

composition of plasma

90% water,8%proteins,minerals,glucose,amino acids,lipids

6

what are the proteins present in the plasma

fibrinogen: clotting factor produced by the liver
globulins: defence mechanism( alpha,beta and gamma. gamma are ANTIBODIES)
albumins: help in osmotic balance and blood volume by controlling the osmotic pressure

7

the minerals present in plasma

na,ca,mg,hco3,cl

8

plasma without clotting factor

serum

9

the formed elements

erythrocytes, leucocytes, thrombocytes

10

rbc count

most abundant, 5 to 5.5 million in mm-3 of blood

11

shape of rbc

biconcave and no nucleus,no mitochondria er ribosomes,centrioles

exceptions: camel and llama. they have oval and nucleus

12

advantages of no nucleus in RBC

they have more space for haemoglobin and respire anaerobically, therefore, more oxygen transported

13

role of carbonic anhydrase in RBC

transport of co2

14

quantity of haemoglobin per 100ml of blood

12-16gms

15

erythropoiesis

redbone marrow

16

graveyard of RBC

spleen

17

what is carbamino haemoglobin and carboxyhaemoglobin

co2 and co

18

lifespan of RBC

120 days

19

the oxidation state of fe in haemoglobin

2+

20

low haemoglobin conc

anaemia or iron deficiency anaemia

21

what is pernicious anaemia

low vit b12 , so RBC don't mature

22

wbc colour

colourless

23

wbc count

6000 to 8000 per mm-3

24

wbc shape

rounded or irregular,nucleated can be granulated or granulated. they show ameboid movements and diapedisis

25

formation of wbc

bone marrow
lymp nodes,spleen,thymus,tonsils,peyers patches

26

describe the agranulocytes

1.lymphocytes: 20 to 25% of total wbc. second most numerous and are small cells with a large nucleus.
they are two types b and t lymphocytes which are responsible for immune response in the body
b lymphocytes mature in the bone marrow and t in the thymus. can last days to years

2.monocytes: 2-10% largest wbc and amoeboid in shape.horseshoe shaped nucleus. they enter tissues and become macrophages and phagocytic and engulf bacteria.20 hour life span

27

describe the granulocytes

1.Neutrophils:60-65%many lobed nucleus takes all stains,fine granules most abundant. they show phagocytosis and are present for 4 to 8 hours in blood,5 days in tissues
2.Eosinophils:2-3% bilobed acidic stain coarse granules. the same lifespan as above. have hydrolytic enzymes, peroxidases, antihistamines, lysosomes and fight allergic reactions. also, dissolve clots
3.Basophils: least abundant (0-1%), basic staining granules, trilobed nucleus.secrete serotonin,heparin,histamines(dilation of blood vessels, which increases permeability and lowers blood pressure). lifespan of 8 hours

28

what is leucocytosis

Increase in wbc count

29

platelets count

1.5 lakhs to 3.5 lakhs per mm-3 smallest free element

30

formation of platelets

cell fragments, they are formed from megakaryocytes of bone marrow. oval disc like and lack nuclei